Evidence map›Paper›PMID 25005471›Full record

ReviewDevelopment (Cambridge, England)2014

Harnessing developmental processes for vascular engineering and regeneration.

Kyung Min Park, Sharon Gerecht

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  14. Matrix stiffness primes lymphatic tube formation directed by vascular endothelial growth factor-C.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kyung Min ParkDepartment of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, and The Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.
Sharon GerechtDepartment of Chemical and Biomolecular Engineering, Johns Hopkins Physical Sciences-Oncology Center, and The Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21208, USA gerecht@jhu.edu.

Funding

Engineered Stem Cell Microenvironments for controlled VasculogenesisR01HL107938 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GERECHT, SHARON · 2011 to 2015
$2.1M
NHLBI NIH HHS R01 HL107938
6 · The paper itself

Abstract

The formation of vasculature is essential for tissue maintenance and regeneration. During development, the vasculature forms via the dual processes of vasculogenesis and angiogenesis, and is regulated at multiple levels: from transcriptional hierarchies and protein interactions to inputs from the extracellular environment. Understanding how vascular formation is coordinated in vivo can offer valuable insights into engineering approaches for therapeutic vascularization and angiogenesis, whether by creating new vasculature in vitro or by stimulating neovascularization in vivo. In this Review, we will discuss how the process of vascular development can be used to guide approaches to engineering vasculature. Specifically, we will focus on some of the recently reported approaches to stimulate therapeutic angiogenesis by recreating the embryonic vascular microenvironment using biomaterials for vascular engineering and regeneration.

Indexed as

Neovascularization, PhysiologicRegenerationAnimalsBiocompatible MaterialsBlood VesselsHumansIntercellular Signaling Peptides and ProteinsTissue EngineeringBiocompatible MaterialsIntercellular Signaling Peptides and ProteinsAngiogenesisBiomaterialsStem cellsTissue engineeringVasculogenesis

Identifiers

PMID25005471
PMCPMC4197623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.