Evidence map›Paper›PMID 25005465›Full record

ReviewSocial psychiatry and psychiatric epidemiology2014

Advances in understanding and treating persecutory delusions: a review.

Daniel Freeman, Philippa Garety

Abstract readReview
In one paragraph

Review in Social psychiatry and psychiatric epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  3. Metacognitive beliefs in individuals at risk for psychosis: a systematic review and meta-analysis of sex differences.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2020
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76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel FreemanDepartment of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK, Daniel.Freeman@psych.ox.ac.uk.
Philippa Garety

Funding

Medical Research Council G0902308
6 · The paper itself

Abstract

purposePersecutory delusions are a central psychotic experience, at the severe end of a paranoia spectrum in the general population. The aim of the review is to provide an introduction to the understanding of persecutory delusions, highlight key putative causal factors that have the potential to be translated into efficacious treatment, and indicate future research directions.

methodsA narrative literature review was undertaken to highlight the main recent areas of empirical study concerning non-clinical and clinical paranoia.

resultsSix main proximal causal factors are identified: a worry thinking style, negative beliefs about the self, interpersonal sensitivity, sleep disturbance, anomalous internal experience, and reasoning biases. Each has plausible mechanistic links to the occurrence of paranoia. These causal factors may be influenced by a number of social circumstances, including adverse events, illicit drug use, and urban environments.

conclusionsThere have been numerous replicated empirical findings leading to a significant advance in the understanding of persecutory delusions, now beginning to be translated into cognitive treatments. The first trials specifically focussed on patients who have persecutory delusions in the context of psychotic diagnoses are occurring. Initial evidence of efficacy is very promising.

Indexed as

AdultAgedAnxietyCognitive Behavioral TherapyCultureDelusionsFemaleHumansInternal-External ControlMaleMiddle AgedParanoid DisordersPsychotic DisordersRisk FactorsSchizophrenia, ParanoidSeverity of Illness Index

Identifiers

PMID25005465
PMCPMC4108844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.