ArticleThe British journal of radiology2014
Non-osseous incidental findings in low-dose whole-body CT in patients with multiple myeloma.
Article in The British journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group.Blood cancer journal · 2017Trial
- Multiple myeloma: What is the most cost-effective imaging strategy for initial detection of bone lesions?Skeletal radiology · 2025Article
- Role of Imaging in Multiple Myeloma: A Potential Opportunity for Quantitative Imaging and Radiomics?Cancers · 2024Review
- Oncologist perspective: role of imaging in myeloma.Skeletal radiology · 2022Review
- Whole-Body Low-Dose Multidetector-Row CT in Multiple Myeloma: Guidance in Performing, Observing, and Interpreting the Imaging Findings.Life (Basel, Switzerland) · 2021Review
- Recommendations for acquisition, interpretation and reporting of whole body low dose CT in patients with multiple myeloma and other plasma cell disorders: a report of the IMWG Bone Working Group.Blood cancer journal · 2018Article
- Advanced Imaging of Multiple Myeloma Bone Disease.Frontiers in endocrinology · 2018Review
- Cardiovascular findings on computed tomography in patients with unclear finding situation and trauma of unknown origin.Medicine · 2017Article
- Radiological findings on irradiation-CT in patients with non metastatic breast cancer.The British journal of radiology · 2017Article
- Renal incidental findings on computed tomography: Frequency and distribution in a large non selected cohort.Medicine · 2017Observational
- [Clinically relevant incidental cardiovascular findings in CT examinations].Der Radiologe · 2017Review
- Incidental findings in the skeletal musculature on computed tomography.The British journal of radiology · 2017Article
- Whole Body Low Dose Computed Tomography Using Third-Generation Dual-Source Multidetector With Spectral Shaping: Protocol Optimization and Literature Review.Dose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to identify the frequency and grading of non-osseous incidental findings (NOIF) in non-contrast whole-body low-dose CT (LDCT) in patients with multiple myeloma.
methodsIn the time period from 2010 to 2013, 93 patients with multiple myeloma were staged by non-contrast whole-body LDCT at our radiological department. LDCT images were analysed retrospectively for NOIF, which also included unsuspected extramedullary manifestation of multiple myeloma. All NOIF were classified as major or clinically significant, moderate or possibly clinically significant and minor or not clinically significant. Medical records were analysed regarding further investigation and follow-up of the identified NOIF.
resultsIn the 93 patients, 295 NOIF were identified (on average, 3.2 NOIF per patient). Most of the NOIF (52.4%) were not clinically significant, 25.8% of the NOIF were possibly clinically significant and 21.8% of the NOIF were clinically significant. Clinically significant NOIF were investigated further by CT after intravenous administration of contrast medium and/or by ultrasound or MRI. In 34 of these cases, extramedullary relapse of myeloma, occult carcinoma or infectious/septic incidental findings were diagnosed (11.5% of all NOIF). In the remaining 10.3% of the NOIF classified as clinically significant, various benign lesions were diagnosed.
conclusionLDCT detected various non-osseous lesions in patients with multiple myeloma. 36.6% of the patients had clinically significant NOIF. Therefore, LDCT examinations in patients with multiple myeloma should be evaluated carefully for the presence of NOIF. ADVANCES IN KNOWLEDGE: LDCT identified several NOIF. A total of 36.6% of patients with multiple myeloma had clinically significant NOIF. Radiologists should analyse LDCT examinations in patients with multiple myeloma not only for bone lesions, but also for lesions in other organs.
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