Evidence map›Paper›PMID 25004366›Full record

ArticleCurrent biology : CB2014

Aging: the blurry line between life and death.

Julia Liu, Toren Finkel

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Julia LiuCenter for Molecular Medicine, National Heart, Lung and Blood Institute, NIH Bethesda, MD 20892, USA.
Toren FinkelCenter for Molecular Medicine, National Heart, Lung and Blood Institute, NIH Bethesda, MD 20892, USA. Electronic address: finkelt@nih.gov.

Funding

Stem cells and agingZIAHL006037 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI FINKEL, TOREN · 2010 to 2016
$6.8M
6 · The paper itself

Abstract

Although historically reactive oxygen species have been implicated as a potential cause of ageing, recent evidence suggests that a modest increase in oxidants can actually extend lifespan. A new study suggests that, in Caenorhabditis elegans, reactive oxygen species regulate longevity through a pathway classically linked to apoptosis.

Indexed as

ApoptosisLongevityAnimalsMitochondriaReactive Oxygen SpeciesReactive Oxygen Species

Identifiers

PMID25004366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.