Evidence map›Paper›PMID 25004279›Full record

ArticleViruses2014

Characterization of a proposed dichorhavirus associated with the citrus leprosis disease and analysis of the host response.

José Luis Cruz-Jaramillo, Roberto Ruiz-Medrano, Lourdes Rojas-Morales, José Abel López-Buenfil, Oscar Morales-Galván, Claudio Chavarín-Palacio, José Abrahán Ramírez-Pool, Beatriz Xoconostle-Cázares

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

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  13. Pest categorisation of Citrus leprosis viruses.EFSA journal. European Food Safety Authority · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

José Luis Cruz-JaramilloDepartamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Av. IPN 2508, Zacatenco 07360, México D.F., Mexico. lcruz@cinvestav.mx.
Roberto Ruiz-MedranoDepartamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Av. IPN 2508, Zacatenco 07360, México D.F., Mexico. rmedrano@cinvestav.mx.
Lourdes Rojas-MoralesLaNSE, Centro de Investigación y de Estudios Avanzados del IPN Av. IPN 2508, Zacatenco 07360, México D.F., Mexico. mlrojas@cinvestav.mx.
José Abel López-BuenfilDepartamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Av. IPN 2508, Zacatenco 07360, México D.F., Mexico. abel.lopez@senasica.gob.mx.
Oscar Morales-GalvánServicio Nacional de Sanidad Inocuidad y Calidad Agroalimentaria, Guillermo Pérez Valenzuela 127, Coyoacán 04100, México D.F., Mexico. oscar.morales@senasica.gob.mx.
Claudio Chavarín-PalacioServicio Nacional de Sanidad Inocuidad y Calidad Agroalimentaria, Guillermo Pérez Valenzuela 127, Coyoacán 04100, México D.F., Mexico. cchavap@gmail.com.
José Abrahán Ramírez-PoolDepartamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Av. IPN 2508, Zacatenco 07360, México D.F., Mexico. jarp1985@hotmail.com.
Beatriz Xoconostle-CázaresDepartamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Av. IPN 2508, Zacatenco 07360, México D.F., Mexico. bxoconos@cinvestav.mx.
Center for Research and Advanced Studies of the National Polytechnic Institute · MXInstituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The causal agents of Citrus leprosis are viruses; however, extant diagnostic methods to identify them have failed to detect known viruses in orange, mandarin, lime and bitter orange trees with severe leprosis symptoms in Mexico, an important citrus producer. Using high throughput sequencing, a virus associated with citrus leprosis was identified, belonging to the proposed Dichorhavirus genus. The virus was termed Citrus Necrotic Spot Virus (CNSV) and contains two negative-strand RNA components; virions accumulate in the cytoplasm and are associated with plasmodesmata-channels interconnecting neighboring cells-suggesting a mode of spread within the plant. The present study provides insights into the nature of this pathogen and the corresponding plant response, which is likely similar to other pathogens that do not spread systemically in plants.

Indexed as

Genome, ViralCitrusFruitGene Expression Regulation, ViralHigh-Throughput Nucleotide SequencingHost-Pathogen InteractionsMexicoNucleocapsidPhylogenyPlant CellsPlant DiseasesPlant ImmunityPlant LeavesPlant VirusesPlasmodesmataRNA Viruses

Identifiers

PMID25004279
PMCPMC4113785
OpenAlexW2030015840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.