Evidence map›Paper›PMID 25004189›Full record

ArticleThe Journal of clinical psychiatry2014

Endpoints in preclinical Alzheimer's disease trials.

Eric M Reiman, Jessica B Langbaum, Pierre N Tariot

Abstract readComment
In one paragraph

Article in The Journal of clinical psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Eric M ReimanBanner Alzheimer's Institute, 901 E Willetta St, Phoenix, AZ 85006 eric.reiman@bannerhealth.com.
Jessica B Langbaum
Pierre N Tariot

Funding

Alzheimer's Prevention Initiative APOE4 TrialUF1AG046150 · NIA · BANNER ALZHEIMER'S INSTITUTE · PI REIMAN, ERIC MICHAEL, TARIOT, PIERRE N. · 2013 to 2013
$33.3M
Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
PET, APOE & the Preclinical Course of Alzheimer's DiseaseR01AG031581 · NIA · BANNER ALZHEIMER'S INSTITUTE · PI CASELLI, RICHARD J., REIMAN, ERIC MICHAEL · 2008 to 2018
$16.6M
Alzheimer's Prevention InitiativeRF1AG041705 · NIA · BANNER ALZHEIMER'S INSTITUTE · PI LOPERA, FRANCISCO, REIMAN, ERIC MICHAEL · 2012 to 2012
$15.3M
NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG19610NIA NIH HHS R01 AG031581NIA NIH HHS RF1 AG041705NIA NIH HHS UF1 AG046150
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllelesChromosome AberrationsDNA Mutational AnalysisGenetic Carrier ScreeningAlzheimer DiseaseGenes, DominantHumansNeuropsychological TestsPresenilin-1Presenilin-1PSEN1 protein, human

Identifiers

PMID25004189
PMCPMC4459723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.