Evidence map›Paper›PMID 25003711›Full record

ReviewNeuroscience2014

Unraveling the secrets of white matter--bridging the gap between cellular, animal and human imaging studies.

K B Walhovd, H Johansen-Berg, R T Káradóttir

Abstract readReview
In one paragraph

Review in Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Quantification of perforant path fibers for early detection of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  16. Article
  17. Review
  18. Morphology of Oligodendroglial Cells.Advances in neurobiology · 2025
    Review
  19. Article
  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K B WalhovdResearch Group for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, POB 1094 Blindern, 0317 Oslo, Norway; Department of Physical Medicine and Rehabilitation, Unit of Neuropsychology, Oslo University Hospital, 0424 Oslo, Norway. Electronic address: k.b.walhovd@psykologi.uio.no.
H Johansen-BergOxford Centre for Functional MRI of the Brain (FMRIB), Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
R T KáradóttirWellcome Trust-Medical Research Council Cambridge Stem Cell Institute, John van Geest Centre for Brain Repair, and Department of Veterinary Medicine, University of Cambridge, Cambridge CB2 1QR, United Kingdom. Electronic address: rk385@cam.ac.uk.

Funding

Wellcome Trust 090955Wellcome Trust 091543/Z/10/ZWellcome Trust WT090955AIA
6 · The paper itself

Abstract

The CNS white matter makes up about half of the human brain, and with advances in human imaging it is increasingly becoming clear that changes in the white matter play a major role in shaping human behavior and learning. However, the mechanisms underlying these white matter changes remain poorly understood. Within this special issue of Neuroscience on white matter, recent advances in our knowledge of the function of white matter, from the molecular level to human imaging, are reviewed. Collaboration between fields is essential to understand the function of the white matter, but due to differences in methods and field-specific 'language', communication is often hindered. In this review, we try to address this hindrance by introducing the methods and providing a basic background to myelin biology and human imaging as a prelude to the other reviews within this special issue.

Indexed as

AnimalsBrain MappingHumansImmunohistochemistryMagnetic Resonance ImagingMicroscopy, ElectronMyelin SheathNeurogliaNeuroimagingWhite MatteranatomyDTIfunctional imagingglial cellmyelinwhite matter

Identifiers

PMID25003711
PMCPMC4155933

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.