Evidence map›Paper›PMID 25003335›Full record

ArticlePloS one2014

Comparing cutaneous research funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases with 2010 Global Burden of Disease results.

Chante Karimkhani, Lindsay N Boyers, David J Margolis, Mohsen Naghavi, Roderick J Hay, Hywel C Williams, Luigi Naldi, Luc E Coffeng, Martin A Weinstock, Cory A Dunnick and 4 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Interventions for the prevention of recurrent erysipelas and cellulitis.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Use of Clinical Public Databases in Hidradenitis Suppurativa Research.Interactive journal of medical research · 2025
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 3 countries.

Chante KarimkhaniCollege of Physicians and Surgeons, Columbia University, New York, New York, United States of America.
Lindsay N BoyersSchool of Medicine, Georgetown University, Washington, District of Columbia, United States of America.
David J MargolisDepartment of Biostatistics and Epidemiology and Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Mohsen NaghaviInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, United States of America.
Roderick J HayDepartment of Dermatology, Kings College Hospital NHS Trust, London, United Kingdom.
Hywel C WilliamsCentre of Evidence Based Dermatology, University of Nottingham, Nottingham, United Kingdom.
Luigi NaldiDepartment of Dermatology, Azienda Ospedaliera papa Giovanni XXIII, Bergamo, Italy.
Luc E CoffengInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, United States of America.
Martin A WeinstockDermatoepidemiology Unit, Veterans Affairs Medical Center Providence, Providence, Rhode Island, United States of America; Department of Dermatology, Rode Island Hospital, Providence, Rhode Island, United States of America; Departments of Dermatology and Epidemiology, Brown University, Providence, Rhode Island, United States of America.
Cory A DunnickDepartment of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America; Dermatology Service, Unites States Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, Colorado, United States of America.
Hannah PedersonUniversity of Colorado School of Medicine, Aurora, Colorado, United States of America.
Theo VosInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, United States of America.
Christopher J L MurrayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, United States of America.
Robert P DellavalleDepartment of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America; Dermatology Service, Unites States Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, Colorado, United States of America; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Institute for Health Metrics and Evaluation · USColumbia University · USGeorgetown University · USKing's College Hospital · GBOspedale Papa Giovanni XXIII · ITProvidence College · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · USUniversity of Nottingham · GBUniversity of Pennsylvania · USUniversity of Washington · USVA Eastern Colorado Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceDisease burden data helps guide research prioritization.

objectiveTo determine the extent to which grants issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) reflect disease burden, measured by disability-adjusted life years (DALYs) from Global Burden of Disease (GBD) 2010 project.

designTwo investigators independently assessed 15 skin conditions studied by GBD 2010 in the NIAMS database for grants issued in 2013. The 15 skin diseases were matched to their respective DALYs from GBD 2010.

settingThe United States NIAMS database and GBD 2010 skin condition disability data. MAIN OUTCOME(S) AND MEASURE(S): Relationship of NIAMS grant database topic funding with percent total GBD 2010 DALY and DALY rank for 15 skin conditions.

resultsDuring fiscal year 2013, 1,443 NIAMS grants were issued at a total value of $424 million. Of these grants, 17.7% covered skin topics. Of the total skin disease funding, 82% (91 grants) were categorized as "general cutaneous research." Psoriasis, leprosy, and "other skin and subcutaneous diseases" (ie; immunobullous disorders, vitiligo, and hidradenitis suppurativa) were over-represented when funding was compared with disability. Conversely, cellulitis, decubitus ulcer, urticaria, acne vulgaris, viral skin diseases, fungal skin diseases, scabies, and melanoma were under-represented. Conditions for which disability and funding appeared well-matched were dermatitis, squamous and basal cell carcinoma, pruritus, bacterial skin diseases, and alopecia areata. CONCLUSIONS AND RELEVANCE: Degree of representation in NIAMS is partly correlated with DALY metrics. Grant funding was well-matched with disability metrics for five of the 15 studied skin diseases, while two skin diseases were over-represented and seven were under-represented. Global burden estimates provide increasingly transparent and important information for investigating and prioritizing national research funding allocations.

Indexed as

Financing, GovernmentBiomedical ResearchCost of IllnessFemaleGlobal HealthHumansMaleNational Institute of Arthritis and Musculoskeletal and Skin Diseases (U.S.)Persons with DisabilitiesQuality-Adjusted Life YearsSkin DiseasesUnited States

Identifiers

PMID25003335
PMCPMC4086973
OpenAlexW2121910794

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.