SynthesisPloS one2014
Total hip replacement for the treatment of end stage arthritis of the hip: a systematic review and meta-analysis.
Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Feasibility and outcomes of the direct anterior approach in total hip arthroplasty for obese patients: a systematic review.Musculoskeletal surgery · 2026Pooled it
- Outcomes of cemented and hybrid primary total hip arthroplasty for osteoarthritis: A systematic review with narrative synthesis.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Choice of implant combinations in total hip replacement: systematic review and network meta-analysis.BMJ (Clinical research ed.) · 2017Pooled it
- Hybrid versus cemented implants for total hip replacement: a randomised feasibility study with embedded qualitative research.BMC musculoskeletal disorders · 2026Trial
- Trial
- Cost consequences of physiotherapy and orthopaedic referral pathways for knee and hip osteoarthritis in Greenland: a pragmatic decision-analytic study.BMC health services research · 2026Article
- Comparison of ChatGPT and Google in addressing patients' questions on robot-assisted total hip arthroplasty.Joint diseases and related surgery · 2026Article
- CORR Insights®: Readmission Within 90 Days After Primary THA Is Associated With Decreased Improvement in 1-Year Patient-reported Outcome Measures and Increased Reoperation Rates.Clinical orthopaedics and related research · 2025Article
- Comparing general and regional anesthesia in patients undergoing primary total hip arthroplasty: analysis of national health insurance data in Korea.Frontiers in medicine · 2025Article
- Assessing pain management in total joint arthroplasty using the Detroit interventional pain assessment scale-A prospective cohort study.Arthroplasty (London, England) · 2024Article
- Income and Insurance Status Impact Access to Health Care for Hip Osteoarthritis.Arthroscopy, sports medicine, and rehabilitation · 2023Article
- Identification of implant outliers in joint replacement registries.EFORT open reviews · 2023Review
- Statins, bone biology and revision arthroplasty: review of clinical and experimental evidence.Therapeutic advances in musculoskeletal disease · 2020Review
- Simulated Performance of a Xenohybrid Bone Graft (SmartBoneJournal of functional biomaterials · 2019Article
- Effectiveness and Tolerability of Repeated Courses of Viscosupplementation in Symptomatic Hip Osteoarthritis: A Retrospective Observational Cohort Study of High Molecular WeightFrontiers in pharmacology · 2019Article
- Nano-sized AlCell death & disease · 2018Article
- Quality assessment of systematic reviews on total hip or knee arthroplasty using mod-AMSTAR.BMC medical research methodology · 2018Article
- Cortisol inhibits mTOR signaling in avascular necrosis of the femoral head.Journal of orthopaedic surgery and research · 2017Article
- Efficacy of intra-articular magnesium for postoperative analgesia in total hip arthroplasty.Biomedical reports · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEvolvements in the design, fixation methods, size, and bearing surface of implants for total hip replacement (THR) have led to a variety of options for healthcare professionals to consider. The need to determine the most optimal combinations of THR implant is warranted. This systematic review evaluated the clinical effectiveness of different types of THR used for the treatment of end stage arthritis of the hip.
methodsA comprehensive literature search was undertaken in major health databases. Randomised controlled trials (RCTs) and systematic reviews published from 2008 onwards comparing different types of primary THR in patients with end stage arthritis of the hip were included.
resultsFourteen RCTs and five systematic reviews were included. Patients experienced significant post-THR improvements in Harris Hip scores, but this did not differ between impact types. There was a reduced risk of implant dislocation after receiving a larger femoral head size (36 mm vs. 28 mm; RR = 0.17, 95% CI: 0.04, 0.78) or cemented cup (vs. cementless cup; pooled odds ratio: 0.34, 95% CI: 0.13, 0.89). Recipients of cross-linked vs. conventional polyethylene cup liners experienced reduced femoral head penetration and revision. There was no impact of femoral stem fixation and cup shell design on implant survival rates. Evidence on mortality and complications (aseptic loosening, femoral fracture) was inconclusive.
conclusionsThe majority of evidence was inconclusive due to poor reporting, missing data, or uncertainty in treatment estimates. The findings warrant cautious interpretation given the risk of bias (blinding, attrition), methodological limitations (small sample size, low event counts, short follow-up), and poor reporting. Long-term pragmatic RCTs are needed to allow for more definitive conclusions. Authors are encouraged to specify the minimal clinically important difference and power calculation for their primary outcome(s) as well CONSORT, PRISMA and STROBE guidelines to ensure better reporting and more reliable production and assessment of evidence.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.