Evidence map›Paper›PMID 25002970›Full record

ArticleBiosensors2013

The DosS-DosT/DosR Mycobacterial Sensor System.

Santhosh Sivaramakrishnan, Paul R Ortiz de Montellano

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 68 citations in OpenAlex.

  1. Immunoblot-based activity assay for heme-containing histidine kinases.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  2. Protein Architecture and Composition in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Review
  5. Comparative transcriptomic signatures of virulent and attenuatedFrontiers in cellular and infection microbiology · 2025
    Article
  6. The DosR regulon ofFrontiers in cellular and infection microbiology · 2025
    Article
  7. Article
  8. Orphan response regulator NnaR is critical for nitrate and nitrite assimilation inFrontiers in cellular and infection microbiology · 2024
    Article
  9. Article
  10. Metalloprotein enabled redox signal transduction in microbes.Current opinion in chemical biology · 2023
    Review
  11. Antibiotics (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Targeting Non-ReplicatingInternational journal of molecular sciences · 2021
    Review
  14. Article
  15. Review
  16. Hydrogen Sulfide and Carbon Monoxide Tolerance in Bacteria.Antioxidants (Basel, Switzerland) · 2021
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Santhosh SivaramakrishnanDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, CA 94158, USA; santhosh.sivaramakrishnan@ucsf.edu.
Paul R Ortiz de MontellanoDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, CA 94158, USA; santhosh.sivaramakrishnan@ucsf.edu.
University of California, San Francisco · US

Funding

Oxygen Sensors and P450 Monooxygenases in Mycobacertium tuberculosisR01AI074824 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ORTIZ DE MONTELLANO, PAUL R · 2007 to 2016
$4.3M
NIAID NIH HHS R01 AI074824
6 · The paper itself

Abstract

DosS/DosR is a two-component regulatory system in which DosS, a heme-containing sensor also known as DevS, under certain conditions undergoes autophosphorylation and then transfers the phosphate to DosR, a DNA-binding protein that controls the entry of

Indexed as

carbon monoxideDevSdormancyDosRDosSDosTheme-based sensorshypoxiaMycobacterium tuberculosisnitric oxidetwo-component system

Identifiers

PMID25002970
PMCPMC4082495
OpenAlexW2011702801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.