ArticleIranian journal of pediatric hematology and oncology2014
Frequency of Celiac Disease in Children with Beta Thalassemia major.
Article in Iranian journal of pediatric hematology and oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Celiac disease in Iran: a systematic review and meta-analysis.Electronic physician · 2017Article
- Serologic evaluation of celiac disease in patients with beta thalassemia major and control.Gastroenterology and hepatology from bed to bench · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to investigate the frequency of celiac disease in children with β-thalassemia major (B-TM) in Shiraz, southern Iran. MATERIALS AND
methodsIn this study, the prevalence of celiac disease in children with B-TM was evaluated. Children with B-TM were screened for celiac disease by ant-tissue transglutaminase (anti-tTG) IgA antibody, IgA level and anti-tTG IgG. A total of 1500 school healthy children in Shiraz with age/sex matched were selected as control group.
resultsA total of 215 B-TM patients with mean age of 12.7 ± 4.4 years, were included into the study (52.1% was male). None of the patients were positive for anti-tTG IgA. Eight cases were IgA deficient in whom anti-tTG IgG was investigated but none of them were positive for anti-tTG IgG. The finding in control group has a seroprevalence of 2% and biopsy proven disease of 0.6%.
conclusionMany patients with thalassemia major have multiple non specific symptom that are not justifiable with underlying disease and might be due to atypical celiac disease. We didn't find any case of celiac disease among more than 200 children with β-thalassemia major in Shiraz, southern Iran. So it seems reasonable to screen only those who have features, even not classical, of celiac disease.
Indexed as
Identifiers
25002924PMC4083199W2283522293What OpenQuestion holds
Registered trials
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