ArticlePharmacognosy research2014
Exploiting the phenomenal anti-ulcerogenic potential of Talinum portulacifolium ethanolic extract whole plant on Albino Rats: The therapeutic potential of Chinese Herb-mǎ chǐ xiàn kē (Portulacaceae).
Article in Pharmacognosy research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Review on recent advancements in understanding acetylsalicylic acid-induced gastrointestinal injury: mechanisms, medication, and dosage refinement.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Gastroprotective Activities of Aqueous and 80% Methanol Leaf Extracts ofJournal of experimental pharmacology · 2023Article
- Essential Oils Derived fromEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion.Molecules (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUlcerations have been effecting humans and causing major damage in the gastro intestinal tract. A need for development of a flawless anti-ulcer medication was always in the agenda. Thus, the need to conduct a study was provoked.
objectivesThe major objective of the present study is to screen the antiulcer activity of the ethanolic extract of Talinum portulacifolium (Forsk) plant. MATERIALS AND
methodsThe antiulcer activity of the ethanolic extract of T.Z portulacifolium was performed on albino rats. Gastric ulcers were induced by ethanol, pylorus ligated aspirin and histamine induced ulcer models. Omeprazole was used as a standard drug for comparison.
resultsTreatment with the T. portulacifolium plant extract significantly protected the ulceration induced by the three models. The gastric volume, pH of gastric juice, total acidity, free acidity and ulcer index were the parameters estimated and did show significant results. 800 mg/kg extracts of T. portulacifolium did show high significant results as that of standard drug. Percentage protection of 800 mg/kg was 79.9% and the standard drug-treated group did show 84%. So was with total acidity (38.1 + 1.45) and free acidity (16.5 + 0.76).
conclusionThe ethanolic extract of T. portulacifolium plant was found to possess a significant antiulcer activity.
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