ArticleApplied and environmental microbiology2014
Bacillaene and sporulation protect Bacillus subtilis from predation by Myxococcus xanthus.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 135 citations in OpenAlex.
- Contact dependent suppression ofbioRxiv : the preprint server for biology · 2026Article
- Genomic and functional landscape of antimicrobial peptides and lipopeptides from ginger honey-derived Bacillus subtilis.Molecular genetics and genomics : MGG · 2026Article
- Predator avoidance promotes inter-bacterial symbiosis with myxobacteria in polymicrobial communities.bioRxiv : the preprint server for biology · 2026Article
- Genomic Insights into Antimicrobial Biosynthetic Potential ofMicroorganisms · 2026Article
- Predator avoidance promotes interbacterial symbiosis with myxobacteria in polymicrobial communities.The ISME journal · 2026Article
- Plipastatin is a shared good by Bacillus subtilis during combating Fusarium spp.FEMS microbiology ecology · 2025Article
- Bacillus subtilis ensures high spore quality in competition with Salmonella Typhimurium via the SigB-dependent pathway.The ISME journal · 2025Article
- Secondary Metabolites fromCurrent research in microbial sciences · 2025Review
- Subtilosin A production is influenced by surfactin levels inmicroLife · 2025Article
- Bacillus velezensis BE2 controls wheat and barley diseases by direct antagonism and induced systemic resistance.Applied microbiology and biotechnology · 2024Article
- Two Strains of EndophyticIndian journal of microbiology · 2024Article
- Comparative genomic analysis ofFrontiers in microbiology · 2024Article
- Substrate specificity of a ketosynthase domain involved in bacillaene biosynthesis.Beilstein journal of organic chemistry · 2024Article
- Pectic homogalacturonan sensed byiScience · 2023Article
- Selective inhibition of the amyloid matrix of Escherichia coli biofilms by a bifunctional microbial metabolite.NPJ biofilms and microbiomes · 2023Article
- Signatures of kin selection in a natural population of the bacteriaEvolution letters · 2023Article
- Isolation and Identification of Endophytic BacteriaBiology · 2023Article
- Two reasons to kill: predation and kin discrimination in myxobacteria.Microbiology (Reading, England) · 2023Review
- Predatory Strategies ofMicroorganisms · 2023Article
- The Endophytic Root Microbiome Is Different in Healthy and Ralstonia solanacearum-Infected Plants and Is Regulated by a Consortium Containing Beneficial Endophytic Bacteria.Microbiology spectrum · 2023Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Myxococcus xanthus and Bacillus subtilis are common soil-dwelling bacteria that produce a wide range of secondary metabolites and sporulate under nutrient-limiting conditions. Both organisms affect the composition and dynamics of microbial communities in the soil. However, M. xanthus is known to be a predator, while B. subtilis is not. A screen of various prey led to the finding that M. xanthus is capable of consuming laboratory strains of B. subtilis, while the ancestral strain, NCIB3610, was resistant to predation. Based in part on recent characterization of several strains of B. subtilis, we were able to determine that the pks gene cluster, which is required for production of bacillaene, is the major factor allowing B. subtilis NCIB3610 cells to resist predation by M. xanthus. Furthermore, purified bacillaene was added exogenously to domesticated strains, resulting in resistance to predation. Lastly, we found that M. xanthus is incapable of consuming B. subtilis spores even from laboratory strains, indicating the evolutionary fitness of sporulation as a survival strategy. Together, the results suggest that bacillaene inhibits M. xanthus predation, allowing sufficient time for development of B. subtilis spores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.