Evidence map›Paper›PMID 25001854›Full record

ArticleTrends in microbiology2014

Porphyromonas gingivalis neutrophil manipulation: risk factor for periodontitis?

Richard P Darveau

Abstract readComment
In one paragraph

Article in Trends in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Richard P DarveauDepartment of Periodontics, School of Dentistry, University of Washington, Seattle, WA 98195, USA. Electronic address: rdarveau@u.washington.edu.

Funding

P. GINGIVALIS LPS-MODULATION OF INNATE HOST DEFENSER01DE012768 · NIDCR · UNIVERSITY OF WASHINGTON · PI DARVEAU, RICHARD PETERS · 1999 to 2014
$5.0M
NIDCR NIH HHS R01 DE012768
6 · The paper itself

Abstract

Defining the contribution of individual members of dysbiotic host-associated bacterial communities has been difficult. The recent paper by Maekawa et al. in Cell Host & Microbe describes bacterial manipulation of neutrophil responses by Porphyromonas gingivalis as a mechanism that contributes to forming a dysbiotic community.

Indexed as

AnimalsDysbiosisPeriodontitisPorphyromonas gingivalisReceptor, Anaphylatoxin C5aToll-Like Receptor 2Receptor, Anaphylatoxin C5aToll-Like Receptor 2

Identifiers

PMID25001854
PMCPMC4132835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.