ArticleThe American journal of gastroenterology2014
Microscopic colitis or functional bowel disease with diarrhea: a French prospective multicenter study.
Article in The American journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 88 citations in OpenAlex.
- A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Efficacy and Safety ofNutrients · 2022Trial
- Sertraline-Associated Microscopic Colitis Flare in Pregnancy.ACG case reports journal · 2026Article
- Cholecystectomy and the risk of microscopic colitis: a systematic review and meta-analysis.Therapeutic advances in gastroenterology · 2025Article
- Article
- Effect of a probiotic formula on gastrointestinal health, immune responses and metabolic health in adults with functional constipation or functional diarrhea.Frontiers in nutrition · 2023Article
- Loose ends in the differential diagnosis of IBS-like symptoms.Frontiers in medicine · 2023Article
- The Epidemiology of Microscopic Colitis in Olmsted County, Minnesota: Population-Based Study From 2011 to 2019.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Article
- Diagnosis and Management of Microscopic Colitis in Pediatric Patients.Paediatric drugs · 2022Review
- Insights into the underlying mechanisms and clinical management of microscopic colitis in relation to other gastrointestinal disorders.Gastroenterology report · 2022Review
- European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations.United European gastroenterology journal · 2021Article
- Rational investigations in irritable bowel syndrome.Frontline gastroenterology · 2020Article
- Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study.British journal of cancer · 2019Article
- Management of microscopic colitis: challenges and solutions.Clinical and experimental gastroenterology · 2019Review
- Prevalence, Pathogenesis, Diagnosis, and Management of Microscopic Colitis.Gut and liver · 2018Review
- High prevalence of irritable bowel syndrome-type symptoms in microscopic colitis: implications for treatment.Therapeutic advances in gastroenterology · 2018Article
- Fatigue and its associated factors in microscopic colitis.Therapeutic advances in gastroenterology · 2018Article
- Microscopic Colitis: A Review of Collagenous and Lymphocytic Colitis.Gastroenterology & hepatology · 2017Article
- Irritable bowel syndrome diagnosis and management: A simplified algorithm for clinical practice.United European gastroenterology journal · 2017Review
- Incidence, Clinical Presentation, and Associated Factors of Microscopic Colitis in Northern France: A Population-Based Study.Digestive diseases and sciences · 2017Article
- Drug Exposure and the Risk of Microscopic Colitis: A Critical Update.Drugs in R&D · 2017Review
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Authors and funding
17 authors at 10 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo describe the characteristics of a cohort of patients with microscopic colitis (MC; lymphocytic (LC) or collagenous (CC) colitis) and to compare them with patients with functional bowel disorder with diarrhea (FBD-D).
methodsBetween September 2010 and June 2012, patients fulfilling the following inclusion criteria were prospectively included in 26 centers in France: (i) having at least three bowel movements daily with change in stool consistency; (ii) duration of abnormal bowel habit >4 weeks; and (iii) normal or near-normal colonoscopy. Each patient underwent a colonoscopy and colonic biopsies. We compared the demographic, clinical, biological, and etiological characteristic of patients with MC (CC and LC) with those of control patients with FBD-D.
resultsA total of 433 patients were included: 129 with MC (87 LC and 42 CC), 23 with another organic disease, and 278 with FDB-D, including patients with diarrhea and abdominal pain who met the criteria of Rome III (irritable bowel syndrome with diarrhea) and patients with functional diarrhea without abdominal pain. Logistic regression analysis identified the following independent predictors of MC: age >50 years (odds ratio (OR)=3.1, 95% confidence interval (CI)=1.6-5.9), presence of nocturnal stools (OR=2, 95% CI=1.1-3.9), weight loss (OR=2.5, 95% CI=1.3-4.7), duration of diarrhea <12 months (OR=2.0, 95% CI=1.1-3.5), recent introduction of new drugs (OR=3.7, 95% CI=2.1-6.6; P<0.0001), and the presence of a known autoimmune disorder (OR=5.5, 95% CI=2.5-12).
conclusionsAge >50 years, the presence of nocturnal stools, weight loss, the introduction of a new drug, and the presence of a known autoimmune disease increase the probability of MC and thus the indication for colonoscopy with biopsies.
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