ReviewThe Journal of general virology2014
Laboratory animal models to study foot-and-mouth disease: a review with emphasis on natural and vaccine-induced immunity.
Review in The Journal of general virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Foot-and-mouth disease virus-derived dendrimer peptides induce germinal center-dependent antibody responses and IgG1 plasma cell differentiation in mice.Scientific reports · 2026Article
- Sterility, safety, and preventive efficacy of three polyvalent hyperimmune sera against bacterial infection in a white mouse challenge model.Frontiers in veterinary science · 2026Article
- Oral levamisole as a route-decoupled adjunct to intramuscular foot-and-mouth disease vaccination: a two-species evaluation.Frontiers in veterinary science · 2026Article
- Qualitative Risk Assessment of Foot-and-Mouth Disease Virus Introduction and Transmission to Dairy Farms via Raw Milk Transportation in Thailand: A Scenario-Based Approach.Veterinary sciences · 2025Article
- Assessment of PRRSV and PCV2 seroprevalence and antigen prevalence in minipigs at laboratory-animal production facilities.Journal of advanced veterinary and animal research · 2024Article
- Article
- Recombinant-attenuated Salmonella enterica serovar Choleraesuis vector expressing the PlpE protein of Pasteurella multocida protects mice from lethal challenge.BMC veterinary research · 2023Article
- Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1).PLoS pathogens · 2022Article
- Generating a Heat-Tolerance Mouse Model.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Vaccines as a Strategy to Control Trichinellosis.Frontiers in microbiology · 2022Review
- Ribavirin as a curative and prophylactic agent against foot and mouth disease virus infection in C57BL/6 suckling and adult mice model.Virusdisease · 2021Article
- Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice.Viruses · 2021Article
- Transboundary Animal Diseases, an Overview of 17 Diseases with Potential for Global Spread and Serious Consequences.Animals : an open access journal from MDPI · 2021Review
- A 5-Year Review of Senecavirus A in China since Its Emergence in 2015.Frontiers in veterinary science · 2020Review
- A New Cage-Like Particle Adjuvant Enhances Protection of Foot-and-Mouth Disease Vaccine.Frontiers in veterinary science · 2020Article
- Immunogenicity of a Dendrimer BFrontiers in veterinary science · 2020Article
- Optimized Adenoviral Vector That Enhances the Assembly of FMDV O1 Virus-Like ParticlesFrontiers in microbiology · 2020Article
- Characterization of the FMDV-serotype-O isolates collected during 1962 and 1997 discloses new topotypes, CEY-1 and WCSA-1, and six new lineages.Scientific reports · 2019Article
- Adaptive Immune Responses following Senecavirus A Infection in Pigs.Journal of virology · 2018Article
- Contributions of Farm Animals to Immunology.Frontiers in veterinary science · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Laboratory animal models have provided valuable insight into foot-and-mouth disease virus (FMDV) pathogenesis in epidemiologically important target species. While not perfect, these models have delivered an accelerated time frame to characterize the immune responses in natural hosts and a platform to evaluate therapeutics and vaccine candidates at a reduced cost. Further expansion of these models in mice has allowed access to genetic mutations not available for target species, providing a powerful and versatile experimental system to interrogate the immune response to FMDV and to target more expensive studies in natural hosts. The purpose of this review is to describe commonly used FMDV infection models in laboratory animals and to cite examples of when these models have failed or successfully provided insight relevant for target species, with an emphasis on natural and vaccine-induced immunity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.