ArticleWorld journal of surgical oncology2014
Relationship between hypoparathyroidism and the number of parathyroid glands preserved during thyroidectomy.
Article in World journal of surgical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
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Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- What are the real rates of temporary hypoparathyroidism following thyroidectomy? It is a matter of definition: a systematic review.Endocrine · 2021Pooled it
- Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism.Archives of endocrinology and metabolism · 2018Guideline
- Risk factors and outcomes of incidental parathyroidectomy in thyroidectomy: A systematic review and meta-analysis.PloS one · 2018Pooled it
- Complications of Trans-oral Endoscopic Thyroidectomy Vestibular Approach: A Systematic Review.In vivo (Athens, Greece)Pooled it
- Article
- Impact of intraoperative parathyroid identification and accidental removal on post-thyroidectomy hypocalcemia: a single-center 15-year experience.BMC surgery · 2026Article
- Calculation of postoperative parathyroid hormone level using indocyanine green angiography during robotic total thyroidectomy: equivalent function hypothesis.Surgical endoscopy · 2026Article
- Impact of parathyroid gland classification on hypoparathyroidism following total thyroidectomy with central neck dissection for differentiated thyroid cancer.Annals of medicine · 2025Article
- Optimizing Parathyroid Preservation in Thyroidectomy: The Burjeel Protocol Utilizing Intraoperative Indocyanine Green Near-Infrared Fluorescence Imaging.Biomedicines · 2025Article
- The predictive role of intraoperative parathyroid hormone measurement on postoperative parathyroid function in patients undergoing total thyroidectomy.Scientific reports · 2024Article
- Hypoparathyroidism after total thyroidectomy: reactive to symptoms supplementation.BMC surgery · 2024Article
- Risk Factors for Transient Hypoparathyroidism after Total Thyroidectomy: Insights from a Cohort Analysis.Journal of clinical medicine · 2024Article
- Factors affecting the rates of incidental parathyroidectomy during thyroidectomy.Annals of the Royal College of Surgeons of England · 2024Article
- Ultrasound characteristics of normal parathyroid glands and analysis of the factors affecting their display.BMC medical imaging · 2024Article
- Patient satisfaction and operator proficiency in gasless transaxillary endoscopic thyroidectomy under IONM: a retrospective cohort study.Frontiers in endocrinology · 2024Article
- Impact of Clinico Pathological and Surgical Related Risk Factor in Post Operative Hypoparathyroidism in Total Thyroidectomy Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Incidence and risk factors of hypoparathyroidism and hypocalcemia after hemithyroidectomy.Langenbeck's archives of surgery · 2023Observational
- Surgical tips and techniques to avoid complications of thyroid surgery.Innovative surgical sciences · 2022Review
- The utility of indocyanine green (ICG) for the identification and assessment of viability of the parathyroid glands during thyroidectomy.Updates in surgery · 2022Observational
- European Expert Consensus on Practical Management of Specific Aspects of Parathyroid Disorders in Adults and in Pregnancy: Recommendations of the ESE Educational Program of Parathyroid Disorders.European journal of endocrinology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between the number of parathyroid glands preserved and hypoparathyroidism is not well understood. We sought to determine the number of parathyroid glands that need to be preserved to prevent hypoparathyroidism.
methodsWe analyzed 454 patients who underwent total thyroidectomy for papillary thyroid carcinoma. We analyzed the frequency of hypoparathyroidism according to the number of parathyroid glands preserved.
resultsIncidental parathyroidectomy occurred in 19.8% of the patients; one parathyroid gland in 17.6%, two in 1.5%, and three in 0.7%. Transient hypoparathyroidism was increased when incidental parathyroidectomy occurred (odds ratio 1.83, 95% confidence interval 1.04 to 3.23, P = 0.036) on multivariate regression analysis, but was not influenced by the actual number of parathyroid glands removed. There was no relationship between the number of parathyroid glands preserved and permanent hypoparathyroidism (P = 0.147).
conclusionsPreservation of all parathyroid glands decreases transient hypoparathyroidism compared with when three or fewer glands are preserved, but does not affect permanent hypoparathyroidism. During total thyroidectomy, preserving at least one parathyroid gland with an intact blood supply appears to be sufficient to prevent permanent hypoparathyroidism when autotransplantation is not performed.
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