ArticleInternational urology and nephrology2014
Effect of continuous positive airway pressure on serum cystatin C among obstructive sleep apnea syndrome patients.
Article in International urology and nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Association between elevated cystatin C levels and obstructive sleep apnea hypopnea syndrome: a systematic review and updated meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Meta-analysis of the effects of CPAP therapy on estimated glomerular filtration rate in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Pooled it
- Effect of positive airway pressure on glomerular filtration rate in patients with sleep-disordered breathing: a meta-analysis.Sleep & breathing = Schlaf & Atmung · 2017Pooled it
- Evaluating cystatin-C and monocyte-to-high-density lipoprotein cholesterol ratio as indicators of obstructive sleep apnea severity in male patients.Frontiers in cardiovascular medicine · 2025Article
- Bcl-2 19-kDa Interacting Protein 3 (BNIP3)-Mediated Mitophagy Attenuates Intermittent Hypoxia-Induced Human Renal Tubular Epithelial Cell Injury.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Changes of circulating biomarkers of inflammation and glycolipid metabolism by CPAP in OSA patients: a meta-analysis of time-dependent profiles.Therapeutic advances in chronic disease · 2022Article
- Association between Serum Cystatin C levels and long-term cardiovascular outcomes and all-cause mortality in older patients with obstructive sleep apnea.Frontiers in physiology · 2022Article
- Glomerular filtration rate in patients with obstructive sleep apnea: the influence of cystatin-C-based estimations and comorbidity.Journal of thoracic disease · 2020Article
- Intermittent hypoxia enhances the tumor programmed death ligand 1 expression in a mouse model of sleep apnea.Annals of translational medicine · 2019Article
- Serum levels of NGAL and cystatin C as markers of early kidney dysfunction in patients with obstructive sleep apnea syndrome.Sleep & breathing = Schlaf & Atmung · 2019Article
- Telmisartan attenuates kidney apoptosis and autophagy-related protein expression levels in an intermittent hypoxia mouse model.Sleep & breathing = Schlaf & Atmung · 2019Article
- Elevated Serum Markers of Acute Kidney Injury in Patients With Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Biomarkers of Alzheimer Disease in Children with Obstructive Sleep Apnea: Effect of Adenotonsillectomy.Sleep · 2016Article
- Cystatin C Levels in Middle-Aged Patients with Obstructive Sleep Apnea Syndrome.Pulmonary medicine · 2016Article
- Obstructive Sleep Apnoea and Vascular Disease in Patients with Type 2 Diabetes.European endocrinology · 2015Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of the present study was to evaluate the influence of continuous positive airway pressure (CPAP) on serum cystatin C, a novel biomarker of early renal impairment, among obstructive sleep apnea (OSA) patients. MATERIALS AND
methodsNewly diagnosed severe OSA patients who treated with CPAP for 3 months were enrolled from two sleep laboratories. Serum biomarkers of renal impairment, cystatin C, creatinine and estimated glomerular filtration rate (eGFR), were detected before and after CPAP treatment.
resultsA total of 39 severe OSA patients were enrolled, 29 (74.4 %) were male, and mean age was 51.2 ± 12.2 years. After CPAP treatment, there were no changes of creatinine and eGFR (77.80 ± 20.00 vs. 75.3 ± 16.60 and 98.69 ± 31.74 vs. 100.20 ± 28.30, all p > 0.05), but cystatin C declined significantly (0.87 ± 0.18 vs. 0.77 ± 0.21, p = 0.000).
conclusionCPAP can decrease cystatin C levels among severe OSA patients and may prevent the latent renal impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.