Evidence map›Paper›PMID 25000558›Full record

ArticleAIDS (London, England)2014

Sexual risk behaviour and viral suppression among HIV-infected adults receiving medical care in the United States.

Christine L Mattson, Mark Freedman, Jennifer L Fagan, Emma L Frazier, Linda Beer, Ping Huang, Eduardo E Valverde, Christopher Johnson, Catherine Sanders, A D McNaghten and 6 more

Abstract read
In one paragraph

Article in AIDS (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Christine L MattsonaDivision of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC) bICF International, Inc, assigned full-time to the Division of HIV/AIDS Prevention, CDC cDivision of Global HIV/AIDS, Center for Global Health, CDC dEmory University eNational Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC fDivision of Global Disease Detection and Emergency Response, Center for Global Health, CDC, Atlanta, Georgia, USA.
Mark Freedman
Jennifer L Fagan
Emma L Frazier
Linda Beer
Ping Huang
Eduardo E Valverde
Christopher Johnson
Catherine Sanders
A D McNaghten
Patrick Sullivan
Amy Lansky
Jonathan Mermin
James Heffelfinger
Jacek Skarbinski
Medical Monitoring Project

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the prevalence and association of sexual risk behaviours and viral suppression among HIV-infected adults in the United States.

designCross-sectional analysis of weighted data from a probability sample of HIV-infected adults receiving outpatient medical care. The facility and patient response rates were 76 and 51%, respectively.

methodsWe analysed 2009 interview and medical record data. Sexual behaviours were self-reported in the past 12 months. Viral suppression was defined as all viral load measurements in the medical record during the past 12 months less than 200 copies/ml.

resultsAn estimated 98 022 (24%) HIV-infected adults engaged in unprotected vaginal or anal sex; 50 953 (12%) engaged in unprotected vaginal or anal sex with at least one partner of negative or unknown HIV status; 23 933 (6%) did so while not virally suppressed. Persons who were virally suppressed were less likely than persons who were not suppressed to engage in vaginal or anal sex [prevalence ratio, 0.88; 95% confidence interval (CI), 0.82-0.93]; unprotected vaginal or anal sex (prevalence ratio, 0.85; 95% CI, 0.73-0.98); and unprotected vaginal or anal sex with a partner of negative or unknown HIV status (prevalence ratio, 0.79; 95% CI, 0.64-0.99).

conclusionThe majority of HIV-infected adults receiving medical care in the U.S. did not engage in sexual risk behaviours that have the potential to transmit HIV, and of the 12% who did, approximately half were not virally suppressed. Persons who were virally suppressed were less likely than persons who were not suppressed to engage in sexual risk behaviours.

Indexed as

Risk-TakingAdolescentAdultCross-Sectional StudiesFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedOutpatientsPrevalenceRNA, ViralSelf ReportSexual BehaviorUnited StatesRNA, Viral

Identifiers

PMID25000558
PMCPMC4004641

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.