ArticleNeuropsychology2015
The role of low cognitive effort and negative symptoms in neuropsychological impairment in schizophrenia.
Article in Neuropsychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The cognitive model of negative symptoms: a systematic review and meta-analysis of the dysfunctional belief systems associated with negative symptoms in schizophrenia spectrum disorders.Psychological medicine · 2025Pooled it
- Victoria Symptom Validity Test: A Systematic Review and Cross-Validation Study.Neuropsychology review · 2021Pooled it
- A Meta-Analysis of Neuropsychological Effort Test Performance in Psychotic Disorders.Neuropsychology review · 2020Pooled it
- Defeatist Performance Beliefs, Negative Symptoms, and Functional Outcome in Schizophrenia: A Meta-analytic Review.Schizophrenia bulletin · 2016Pooled it
- The Course of Neurocognitive Changes in Acute Psychosis: Relation to Symptomatic Improvement.PloS one · 2016Trial
- Elevated defeatist performance beliefs predict state increases in negative symptoms in daily life in clinical high-risk for psychosis youth: implications for mobile health treatments.European archives of psychiatry and clinical neuroscience · 2026Article
- Psychosis-proneness is associated with reduced cognitive error-monitoring during instrumental learning.Schizophrenia research. Cognition · 2026Article
- Why clinical neuropsychology matters in schizophrenia care.Frontiers in psychology · 2025Review
- The Role of Defeatist Performance Beliefs in State Fluctuations of Negative Symptoms in Schizophrenia Measured in Daily Life via Ecological Momentary Assessment.Schizophrenia bulletin · 2024Article
- Reduced Reward Processing in Schizophrenia: A Comprehensive EEG Event-Related Oscillation Study.Brain topography · 2024Article
- Deconstructing Mechanisms of Abnormal Categorical Perception of Emotional Facial Expressions in Schizophrenia Patients.Psychiatry investigation · 2022Article
- Persistent negative symptoms in youth at clinical high risk for psychosis: A longitudinal study.Schizophrenia research · 2021Article
- Clarifying the direction of impact of negative symptoms and neurocognition on prospective work functioning in psychosis: A 20-year longitudinal study.Schizophrenia research · 2020Article
- Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine AFrontiers in pharmacology · 2018Article
- Preclinical Models to Investigate Mechanisms of Negative Symptoms in Schizophrenia.Schizophrenia bulletin · 2017Review
- A Transdiagnostic Review of Negative Symptom Phenomenology and Etiology.Schizophrenia bulletin · 2017Review
- Neural mechanisms of mood-induced modulation of reality monitoring in schizophrenia.Cortex; a journal devoted to the study of the nervous system and behavior · 2017Article
- The current conceptualization of negative symptoms in schizophrenia.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2017Article
- A Psychometric Comparison of the Clinical Assessment Interview for Negative Symptoms and the Brief Negative Symptom Scale.Schizophrenia bulletin · 2016Article
- Pupillary Responses as a Biomarker of Diminished Effort Associated With Defeatist Attitudes and Negative Symptoms in Schizophrenia.Biological psychiatry · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTwo experiments were conducted to examine whether insufficient effort, negative symptoms (e.g., avolition, anhedonia), and psychological variables (e.g., anhedonia and perception of low cognitive resources) predict generalized neurocognitive impairment in individuals with schizophrenia (SZ).
methodIn Experiment 1, participants included 97 individuals with SZ and 63 healthy controls (CN) who completed the Victoria Symptom Validity Test (VSVT), the MATRICS Consensus Cognitive Battery (MCCB), and self-report anhedonia questionnaires. In Experiment 2, participants included 46 individuals with SZ and 33 CN who completed Green's Word Memory Test (WMT), the MCCB, and self-reports of anhedonia, defeatist performance beliefs, and negative expectancy appraisals.
resultsRESULTS indicated that a low proportion of individuals with SZ failed effort testing (1.0% Experiment 1; 15.2% Experiment 2); however, global neurocognitive impairment was significantly predicted by low effort and negative symptoms.
conclusionsFindings indicate that low effort does not threaten the validity of neuropsychological test results in the majority of individuals with schizophrenia; however, effort testing may be useful in SZ patients with severe negative symptoms who may be more likely to put forth insufficient effort due to motivational problems. Although the base rate of failure is relatively low, it may be beneficial to screen for insufficient effort in SZ and exclude individuals who fail effort testing from pharmacological or cognitive remediation trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.