Evidence map›Paper›PMID 25000260›Full record

ArticlePloS one2014

Opportunities for tuberculosis diagnosis and prevention among persons living with HIV: a cross-sectional study of policies and practices at four large Ryan White Program-Funded HIV clinics.

Lisa Pascopella, Julie Franks, Suzanne M Marks, Katya Salcedo, Kjersti Schmitz, Paul W Colson, Yael Hirsch-Moverman, Jennifer Flood, Jennifer Sayles

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Isoniazid therapy for Mycobacterium tuberculosis infection in HIV clinics, Los Angeles, California.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lisa PascopellaTuberculosis Control Branch, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, California, United States of America.
Julie FranksThe International Center for AIDS Care and Treatment Programs (ICAP)/Columbia University Mailman School of Public Health, New York, New York, United States of America.
Suzanne M MarksDivision of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Katya SalcedoTuberculosis Control Branch, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, California, United States of America.
Kjersti SchmitzThe International Center for AIDS Care and Treatment Programs (ICAP)/Columbia University Mailman School of Public Health, New York, New York, United States of America.
Paul W ColsonThe International Center for AIDS Care and Treatment Programs (ICAP)/Columbia University Mailman School of Public Health, New York, New York, United States of America.
Yael Hirsch-MovermanThe International Center for AIDS Care and Treatment Programs (ICAP)/Columbia University Mailman School of Public Health, New York, New York, United States of America.
Jennifer FloodTuberculosis Control Branch, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Richmond, California, United States of America.
Jennifer SaylesOffice of AIDS Programs and Policy, Los Angeles County Department of Public Health, Los Angeles, California, United States of America.
Columbia University · USCalifornia Department of Public Health · USCenters for Disease Control and Prevention · USLos Angeles County Department of Public Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe describe the frequency and attributes of tuberculosis testing and treatment at four publicly-funded HIV clinics.

methodsWe abstracted medical records from a random sample of 600 HIV-infected patients having at least one clinic visit in 2009 at four clinics in New York and Los Angeles Metropolitan Statistical areas. We described testing and treatment for tuberculosis infection (TBI), 2008-2010, and estimated adjusted odds ratios (aORs). We interviewed key informants and described clinic policies and practices.

resultsOf 600 patients, 500 were eligible for testing, and 393 (79%) were tested 2008-2010; 107 (21%) did not receive at least one tuberculin skin test or interferon gamma release assay. Results were positive in 20 (5%) patients, negative in 357 (91%), and unknown in 16 (4%). Fourteen (70%) of 20 patients with TBI initiated treatment at the clinics; only three were documented to have completed treatment. Three hundred twenty three (54%) patients had chest radiography, 346 (58%) had tuberculosis symptom screening, and three had tuberculosis disease (117 per 100,000 person-years, 95% confidence interval (CI) = 101-165). Adjusting for site, non-Hispanic ethnicity (aOR = 4.9, 95% CI = 2.6-9.5), and employment (aOR = 1.9, 95% CI = 1.0-3.4) were associated with TBI testing; female gender (aOR = 2.0, 95% CI = 1.4-3.3), non-black race (aOR = 1.7, 95% CI = 1.3-2.5), and unemployment (aOR = 1.5, 95% CI = 1.1-2.1) were associated with chest radiography. Clinics evaluated TBI testing performance annually and identified challenges to TB prevention.

conclusionsStudy clinics routinely tested patients for TBI, but did not always document treatment. In a population with a high TB rate, ensuring treatment of TBI may enhance TB prevention.

Indexed as

PolicyAdolescentAdultAgedAged, 80 and overAmbulatory Care FacilitiesAntiretroviral Therapy, Highly ActiveCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedRadiography, ThoracicTuberculosisYoung Adult

Identifiers

PMID25000260
PMCPMC4084815
OpenAlexW2045971200

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.