Evidence map›Paper›PMID 25000149›Full record

Trial reportInternational journal of environmental research and public health2014

Respiratory effects of fine and ultrafine particles from indoor sources--a randomized sham-controlled exposure study of healthy volunteers.

Vanessa J Soppa, Roel P F Schins, Frauke Hennig, Bryan Hellack, Ulrich Quass, Heinz Kaminski, Thomas A J Kuhlbusch, Barbara Hoffmann, Gudrun Weinmayr

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Early Origins of Chronic Obstructive Pulmonary Disease: Prenatal and Early Life Risk Factors.International journal of environmental research and public health · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Short-Term Effects of Carbonaceous Components in PMInternational journal of environmental research and public health · 2019
    Article
  9. Fine and ultrafine particle doses in the respiratory tract from digital printing operations.Environmental science and pollution research international · 2017
    Article
  10. Exposure to Air Ions in Indoor Environments: Experimental Study with Healthy Adults.International journal of environmental research and public health · 2015
    Article
  11. A Novel High-Throughput Approach to Measure Hydroxyl Radicals Induced by Airborne Particulate Matter.International journal of environmental research and public health · 2015
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vanessa J SoppaIUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany. vanessa.soppa@IUF-Duesseldorf.de.
Roel P F SchinsIUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany. roel.schins@uni-duesseldorf.de.
Frauke HennigIUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany. frauke.hennig@IUF-Duesseldorf.de.
Bryan HellackAir Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58-60, 47229 Duisburg, Germany. hellack@iuta.de.
Ulrich QuassAir Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58-60, 47229 Duisburg, Germany. quass@iuta.de.
Heinz KaminskiAir Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58-60, 47229 Duisburg, Germany. kaminski@iuta.de.
Thomas A J KuhlbuschAir Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58-60, 47229 Duisburg, Germany. tky@iuta.de.
Barbara HoffmannIUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany. barbara.hoffmann@IUF-Duesseldorf.de.
Gudrun WeinmayrIUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany. gudrun.weinmayr@IUF-Duesseldorf.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particulate air pollution is linked to impaired respiratory health. We analyzed particle emissions from common indoor sources (candles burning (CB), toasting bread (TB), frying sausages (FS)) and lung function in 55 healthy volunteers (mean age 33.0 years) in a randomized cross-over controlled exposure study. Lung-deposited particle surface area concentration (PSC), size-specific particle number concentration (PNC) up to 10 µm, and particle mass concentration (PMC) of PM1, PM2.5 and PM10 were determined during exposure (2 h). FEV1, FVC and MEF25%-75% was measured before, 4 h and 24 h after exposure. Wilcoxon-rank sum tests (comparing exposure scenarios) and mixed linear regression using particle concentrations and adjusting for personal characteristics, travel time and transportation means before exposure sessions were performed. While no effect was seen comparing the exposure scenarios and in the unadjusted model, inverse associations were found for PMC from CB and FS in relation to FEV1 and MEF25%-75%. with a change in 10 µg/m3 in PM2.5 from CB being associated with a change in FEV1 of -19 mL (95%-confidence interval:-43; 5) after 4 h. PMC from TB and PNC of UFP were not associated with lung function changes, but PSC from CB was. Elevated indoor fine particles from certain sources may be associated with small decreases in lung function in healthy adults.

Indexed as

AdolescentAdultAir PollutantsAir Pollution, IndoorCross-Over StudiesFemaleForced Expiratory VolumeHealthy VolunteersHumansMaleMaximal Expiratory Flow RateMiddle AgedParticle SizeParticulate MatterVital CapacityYoung AdultAir PollutantsParticulate Matter

Identifiers

PMID25000149
PMCPMC4113851

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.