ArticleDrug and alcohol dependence2014
Problematic substance use in urban adolescents: role of intrauterine exposures to cocaine and marijuana and post-natal environment.
Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- The Enduring Effects of Parental Alcohol, Tobacco, and Drug Use on Child Well-being: A Multilevel Meta-Analysis.Development and psychopathology · 2020Pooled it
- Cannabis use during pregnancy and its relationship with fetal developmental outcomes and psychiatric disorders. A systematic review.Reproductive health · 2020Pooled it
- Alcohol, Marijuana and Other Illicit Drugs Use Throughout Adolescence: Co-occurring Courses and Preadolescent Risk-Factors.Child psychiatry and human development · 2022Article
- Accuracy of five self-report screening instruments for substance use in pregnancy.Addiction (Abingdon, England) · 2019Article
- Do Differences in Learning Performance Precede or Follow Initiation of Marijuana Use?Journal of studies on alcohol and drugs · 2019Article
- Cannabis use during pregnancy: Pharmacokinetics and effects on child development.Pharmacology & therapeutics · 2018Review
- The association of prenatal cocaine exposure, externalizing behavior and adolescent substance use.Drug and alcohol dependence · 2017Article
- Intrauterine exposure to tobacco and executive functioning in high school.Drug and alcohol dependence · 2017Article
- An Ecodevelopmental Exploration of Mediators Between Maltreatment in Childhood and Drug use During Pregnancy.Merrill-Palmer quarterly (Wayne State University. Press) · 2017Article
- Does prenatal cocaine exposure predict adolescent substance use?Neurotoxicology and teratologyArticle
- Prenatal cocaine exposure, early cannabis use, and risky sexual behavior at age 25.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLinkages between intrauterine exposures to cocaine and marijuana and adolescents' problematic substance use have not been fully delineated.
methodsProspective longitudinal study with assessors unaware of intrauterine exposure history followed 157 urban participants from birth until late adolescence. Level of intrauterine exposures was identified by mother's report and infant's meconium. Problematic substance use, identified by the Voice Diagnostic Interview Schedule for Children (V-DISC) or the Audio Computer Assisted Self-Interview (ACASI) and urine assay, was a composite encompassing DSM-IV indication of tolerance, abuse, and dependence on alcohol, marijuana, and tobacco and any use of cocaine, glue, or opiates.
resultsTwenty percent (32/157) of the sample experienced problematic substance use by age 18 years, of whom the majority (22/157) acknowledged abuse, tolerance or dependence on marijuana with or without other substances. Structural equation models examining direct and indirect pathways linking a Cox survival model for early substance initiation to a logistic regression models found effects of post-natal factors including childhood exposure to violence and household substance use, early youth substance initiation, and ongoing youth violence exposure contributing to adolescent problematic substance use.
conclusionWe did not identify direct relationships between intrauterine cocaine or marijuana exposure and problematic substance use, but did find potentially modifiable post-natal risk factors also noted to be associated with problematic substance use in the general population including earlier substance initiation, exposure to violence and to household substance use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.