Evidence map›Paper›PMID 24998473›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2014

Tumor characteristics of breast cancer in predicting axillary lymph node metastasis.

Hsin-Shun Tseng, Li-Sheng Chen, Shou-Jen Kuo, Shou-Tung Chen, Yu-Fen Wang, Dar-Ren Chen

Abstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Observational
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  10. Establishment of risk prediction nomogram for ipsilateral axillary lymph node metastasis in T1 breast cancer.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021
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  14. Predictive Value of Clinicopathological Characteristics for Sentinel Lymph Node Metastasis in Early Breast Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2017
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  16. Experimental Study of Magnetic Multi-Walled Carbon Nanotube-Doxorubicin Conjugate in a Lymph Node Metastatic Model of Breast Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hsin-Shun TsengComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua, Taiwan.
Li-Sheng ChenSchool of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Shou-Jen KuoComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua, Taiwan.
Shou-Tung ChenComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua, Taiwan.
Yu-Fen WangDepartment of Medical Research, Changhua Christian Hospital, Changhua, Taiwan.
Dar-Ren ChenComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTumor characteristics was sought to be related to axillary lymph node metastasis (ALNM), the paramount prognostic factor in patients with invasive breast cancer. This study was aimed to identify the ALNM-associated tumor characteristics and to determine the predictive clinical pathway. MATERIAL AND

methodsData from 1325 patients diagnosed with invasive breast cancer between January 2004 and January 2010 were retrospectively reviewed. The structure equation model (SEM) was used to build the predictive clinical pathway.

resultsAmong the factors found in the final model, the status of human epidermal growth factor receptor 2 is the primary influence on ALNM through histology grade (β=0.18), followed by tumor size (β=0.16). Tumor size was highly relevant to lymphovascular invasion (LVI) and influenced ALNM through LVI (β=0.26), the strongest predictor of ALNM in the final model (β=0.46) and the highest risk of ALNM (odds ratio=9.282; 95% confidence interval: 7.218-11.936).

conclusionsThe structure equation model presented the relation of these important predictors, and might help physicians to assess axillary nodal condition and appropriate surgical procedures.

Indexed as

AxillaBreast NeoplasmsFemaleHumansLogistic ModelsLymphatic MetastasisLymph NodesMiddle AgedModels, BiologicalPrognosis

Identifiers

PMID24998473
PMCPMC4099209

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.