ArticleScientific reports2014
A novel two-step sintering for nano-hydroxyapatite scaffolds for bone tissue engineering.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Bioactivity, hemocompatibility, and inflammatory response of calcium incorporated sulfonated polyether ether ketone on mouse-derived bone marrow cells.Bioscience reports · 2024Article
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- Enzymatically-mineralized double-network hydrogels with ultrahigh mechanical strength, toughness, and stiffness.Theranostics · 2023Article
- Advancement inJournal of environmental health science & engineering · 2022Review
- Microstructural, electrical and biological activity in [Formula: see text] ceramic composites designed for tissue engineering applications.Scientific reports · 2021Article
- Selective Laser Melting of Hydroxyapatite: Perspectives for 3D Printing of Bioresorbable Ceramic Implants.Materials (Basel, Switzerland) · 2021Article
- Nature-inspired topographies on hydroxyapatite surfaces regulate stem cells behaviour.Bioactive materials · 2021Article
- Construction of Inorganic Bulks through Coalescence of Particle Precursors.Nanomaterials (Basel, Switzerland) · 2021Review
- Effects of the Sintering Process on Nacre-Derived Hydroxyapatite Scaffolds for Bone Engineering.Molecules (Basel, Switzerland) · 2020Article
- Three-Dimensional Extrusion Printing of Porous Scaffolds Using Storable Ceramic Inks.Tissue engineering. Part C, Methods · 2020Article
- Injection Molding of 3-3 Hydroxyapatite Composites.Materials (Basel, Switzerland) · 2020Article
- Calcium Phosphate Nanoparticles for Therapeutic Applications in Bone Regeneration.Nanomaterials (Basel, Switzerland) · 2019Review
- Additive manufacturing of bone scaffolds.International journal of bioprinting · 2019Review
- Three-dimensional printing with biomaterials in craniofacial and dental tissue engineering.PeerJ · 2019Article
- Aromatic thermosetting copolyester bionanocomposites as reconfigurable bone substitute materials: Interfacial interactions between reinforcement particles and polymer network.Scientific reports · 2018Article
- Additive Manufacturing with 3D Printing: Progress from Bench to Bedside.The AAPS journal · 2018Review
- Sonochemical synthesis of cellulose/hydroxyapatite nanocomposites and their application in protein adsorption.Scientific reports · 2018Article
- In vitro evaluation of a bone morphogenetic protein‑2 nanometer hydroxyapatite collagen scaffold for bone regeneration.Molecular medicine reports · 2018Article
- Enhancement of osteoblast activity on nanostructured NiTi/hydroxyapatite coatings on additive manufactured NiTi metal implants by nanosecond pulsed laser sintering.International journal of nanomedicine · 2018Article
- Calcium Silicate Improved Bioactivity and Mechanical Properties of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Scaffolds.Polymers · 2017Article
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5 authors.
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Abstract
In this study, nano-hydroxyapatite scaffolds with high mechanical strength and an interconnected porous structure were prepared using NTSS for the first time. The first step was performed using a laser characterized by the rapid heating to skip the surface diffusion and to obtain the driving force for grain boundary diffusion. Additionally, the interconnected porous structure was achieved by SLS. The second step consisted of isothermal heating in a furnace at a lower temperature (T2) than that of the laser beam to further increase the density and to suppress grain growth by exploiting the difference in kinetics between grain-boundary diffusion and grain-boundary migration. The results indicated that the mechanical properties first increased and then decreased as T2 was increased from 1050 to 1250°C. The optimal fracture toughness, compressive strength and stiffness were 1.69 MPam(1/2), 18.68 MPa and 245.79 MPa, respectively. At the optimal point, the T2 was 1100°C, the grain size was 60 nm and the relative density was 97.6%. The decrease in mechanical properties was due to the growth of grains and the decomposition of HAP. The cytocompatibility test results indicated that cells adhered and spread well on the scaffolds. A bone-like apatite layer formed, indicating good bioactivity.
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