Evidence map›Paper›PMID 24997663›Full record

ArticleJournal of dairy science2014

Prediction of pregnancy viability in bovine in vitro-produced embryos and recipient plasma with Fourier transform infrared spectroscopy.

M Muñoz, A Uyar, E Correia, C Díez, A Fernandez-Gonzalez, J N Caamaño, D Martínez-Bello, B Trigal, P Humblot, C Ponsart and 6 more

Abstract read
In one paragraph

Article in Journal of dairy science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. In vitro production significantly reduces metabolic differences among bovine embryos.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

M MuñozCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
A UyarDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, 310 Cedar street, LSOG 304B, New Haven, CT 06520; Department of Computer Engineering, Okan University, Tuzla Kampusu, 34959, Tuzla, Istanbul, Turkey.
E CorreiaCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
C DíezCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
A Fernandez-GonzalezServicios Científico Técnicos (Oviedo), Universidad de Oviedo, 33006 Oviedo, Asturias, Spain.
J N CaamañoCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
D Martínez-BelloU.T.E. Bos-Lugar de Bos, Guísamo 15640 Bergondo, A Coruña, Spain.
B TrigalCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
P HumblotSwedish University of Agricultural Sciences, PO Box 7054, SE75007 Uppsala, Sweden.
C PonsartUnion Nationale des Cooperatives D' Elevage et Insemination Animale (UNCEIA), Department of Research and Development, 13 rue Jouet, 94704 Maisons Alfort, France.
C Guyader-JolyUNCEIA, Station Expérimentale, 484 Chemin Darefin, 38300 Chateauvillain, France.
S CarroceraCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
D MartinCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain.
B Marquant Le GuienneUnion Nationale des Cooperatives D' Elevage et Insemination Animale (UNCEIA), Department of Research and Development, 13 rue Jouet, 94704 Maisons Alfort, France.
E SeliDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, 310 Cedar street, LSOG 304B, New Haven, CT 06520.
E GomezCentro de Biotecnología Animal-Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Camino de Rioseco 1225, La Olla - Deva, 33394 Gijón, Asturias, Spain. Electronic address: egomez@serida.org.

Funding

Regulation of maternal mRNA translation during early developmentR01HD059909 · NICHD · YALE UNIVERSITY · PI SELI, EMRE UTKU · 2011 to 2015
$1.7M
NICHD NIH HHS R01 HD059909NICHD NIH HHS R01HD059909
6 · The paper itself

Abstract

We analyzed embryo culture medium (CM) and recipient blood plasma using Fourier transform infrared (FTIR) metabolomics to predict pregnancy outcome. Individually cultured, in vitro-produced (IVP) blastocysts were transferred to recipients as fresh and vitrified-warmed. Spent CM and plasma samples were evaluated using FTIR. The discrimination capability of the classifiers was assessed for accuracy, sensitivity (pregnancy), specificity (nonpregnancy), and area under the receiver operator characteristic curve (AUC). Within all IVP fresh embryos (birth rate=52%), high AUC were obtained at birth, especially with expanded blastocysts (CM: 0.80±0.053; plasma: 0.89±0.034). The AUC of vitrified IVP embryos (birth rate = 31%) were 0.607±0.038 (CM, expanded blastocysts) and 0.672±0.023 (plasma, all stages). Recipient plasma generally predicted pregnancy outcome better than did embryo CM. Embryos and recipients with improved pregnancy viability were identified, which could increase the economic benefit to the breeding industry.

Indexed as

Pregnancy, AnimalSpectroscopy, Fourier Transform InfraredAnimalsBlastocystCattleCryopreservationCulture MediaEmbryo TransferFemaleFertilization in VitroMetabolomicsModels, BiologicalPlasmaPregnancyPregnancy OutcomeCulture Mediabovineembryopregnancyrecipient

Identifiers

PMID24997663
PMCPMC4208725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.