Evidence map›Paper›PMID 24997399›Full record

ArticleCurrent opinion in microbiology2014

Advanced mass spectrometry technologies for the study of microbial pathogenesis.

Jessica L Moore, Richard M Caprioli, Eric P Skaar

Abstract read
In one paragraph

Article in Current opinion in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. MALDI TIMS IMS Reveals Ganglioside Molecular Diversity within MurineJournal of the American Society for Mass Spectrometry · 2024
    Article
  3. ReducingAnalytical chemistry · 2023
    Article
  4. Prospective on Imaging Mass Spectrometry in Clinical Diagnostics.Molecular & cellular proteomics : MCP · 2023
    Review
  5. Advances in Mass Spectrometry-Metabolomics Based Approaches.Advances in experimental medicine and biology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. QuantitativeBiosensors · 2021
    Article
  11. Article
  12. Article
  13. Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Host-based lipid inflammation drives pathogenesis inProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica L MooreMass Spectrometry Research Center, Vanderbilt University, Nashville, TN, United States.
Richard M CaprioliMass Spectrometry Research Center, Vanderbilt University, Nashville, TN, United States. Electronic address: R.Caprioli@Vanderbilt.edu.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States. Electronic address: Eric.Skaar@Vanderbilt.edu.

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Training (pp 214-245)P41GM103391 · NIGMS · VANDERBILT UNIVERSITY · PI REYZER, MICHELLE L · 2012 to 2020
$17.7M
Chemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0M
Pathobiology of heme inducible transporters in Gram positive pathogensR01AI073843 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2009 to 2025
$5.9M
Mechanism and function of heme-iron utilization in staphylococcal pathogenesisR01AI069233 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2006 to 2020
$5.6M
IMAGING MASS SPECTROMETRY RESEARCH RESOURCE AT VANDERBILT UNIVERSITYP41RR031461 · NCRR · VANDERBILT UNIVERSITY · PI CAPRIOLI, RICHARD M · 2011 to 2011
$2.2M
Imaging the struggle for nutrient metal between host and pathogenR21AI107233 · NIAID · VANDERBILT UNIVERSITY · PI SKAAR, ERIC P · 2013 to 2014
$415k
NCRR NIH HHS P41 RR031461NIAID NIH HHS R01 AI069233NIAID NIH HHS R01 AI073843NIAID NIH HHS R21 AI107233NIDDK NIH HHS P30 DK058404NIGMS NIH HHS P41 GM103391NIGMS NIH HHS P41 GM103391-04NIGMS NIH HHS T32 GM 065086NIGMS NIH HHS T32 GM065086
6 · The paper itself

Abstract

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) has been successfully applied to the field of microbial pathogenesis with promising results, principally in diagnostic microbiology to rapidly identify bacteria based on the molecular profiles of small cell populations. Direct profiling of molecules from serum and tissue samples by MALDI MS provides a means to study the pathogen-host interaction and to discover potential markers of infection. Systematic molecular profiling across tissue sections represents a new imaging modality, enabling regiospecific molecular measurements to be made in situ, in both two-dimensional and three-dimensional analyses. Herein, we briefly summarize work that employs MALDI MS to study the pathogenesis of microbial infection.

Indexed as

Mass SpectrometryAnimalsHost-Pathogen InteractionsHumansMicrobiological TechniquesSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Identifiers

PMID24997399
PMCPMC4125470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.