Evidence map›Paper›PMID 24997267›Full record

ReviewNeuroscience2015

Sensory systems: their impact on C. elegans survival.

Erika Allen, Jing Ren, Yun Zhang, Joy Alcedo

Abstract readReview
In one paragraph

Review in Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. A genome-wide association study implicates the olfactory system inbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. GABA receptors differentially regulate life span and health span inAmerican journal of physiology. Cell physiology · 2019
    Article
  10. Review
  11. Article
  12. A Pipeline for Volume Electron Microscopy of theFrontiers in neural circuits · 2018
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erika Allen *Department of Biological Sciences, Wayne State University, Detroit, MI 48334, USA.
Jing Ren *Department of Organismic and Evolutionary Biology, Center for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Yun ZhangDepartment of Organismic and Evolutionary Biology, Center for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Joy AlcedoDepartment of Biological Sciences, Wayne State University, Detroit, MI 48334, USA.

Funding

Molecular and Cellular Mechanisms of a Neuronal Network that Regulates OlfactoryR01DC009852 · NIDCD · HARVARD UNIVERSITY · PI ZHANG, YUN · 2009 to 2017
$3.5M
NIDCD NIH HHS R01 DC009852NIDCD NIH HHS R01DC009852
6 · The paper itself

Abstract

An animal's survival strongly depends on a nervous system that can rapidly process and integrate the changing quality of its environment and promote the most appropriate physiological responses. This is amply demonstrated in the nematode worm Caenorhabditis elegans, where its sensory system has been shown to impact multiple physiological traits that range from behavior and developmental plasticity to longevity. Because of the accessibility of its nervous system and the number of tools available to study and manipulate its neural circuitry, C. elegans has thus become an important model organism in dissecting the mechanisms through which the nervous system promotes survival. Here we review our current understanding of how the C. elegans sensory system affects diverse physiological traits, whose coordination would be essential for survival under fluctuating environments. The knowledge we derive from the C. elegans studies should provide testable hypotheses in discovering similar mechanisms in higher animals.

Indexed as

LongevityAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsModels, AnimalSensory Receptor CellsCaenorhabditis elegans ProteinsC. elegansdevelopmental plasticityinsulin-like peptideslearninglifespansensory system

Identifiers

PMID24997267
PMCPMC4282626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.