Evidence map›Paper›PMID 24997164›Full record

Trial reportJournal of materials science. Materials in medicine2014

Novel unidirectional porous hydroxyapatite used as a bone substitute for open wedge high tibial osteotomy.

Kenta Uemura, Akihiro Kanamori, Katsuya Aoto, Masashi Yamazaki, Masataka Sakane

Abstract readClinical TrialHistorical Article
In one paragraph

Trial report in Journal of materials science. Materials in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Unidirectional porous beta-tricalcium phosphate and hydroxyapatite artificial bone: a review of experimental evaluations and clinical applications.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2021
    Review
  4. Article
  5. [Management principle and clinical suggestions of osteotomy gap of opening wedge high tibial osteotomy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020
    Review
  6. Angiogenesis and new bone formation in novel unidirectional porous beta-tricalcium phosphate: a histological study.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2019
    Article
  7. Article
  8. Article
  9. Formation of osteon-like structures in unidirectional porous hydroxyapatite substitute.Journal of biomedical materials research. Part B, Applied biomaterials · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenta UemuraDepartment of Orthopaedic Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai Tsukuba, Ibaraki, 305-8575, Japan, sakane-m@tsukuba-seikei.jp.
Akihiro Kanamori
Katsuya Aoto
Masashi Yamazaki
Masataka Sakane

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to clinically and radiologically evaluate the availability, osteoconductivity, and resorption of a novel unidirectional porous hydroxyapatite (UDPHAp) used as an artificial substitute for open wedge high tibial osteotomy (OWHTO). Our hypothesis was that UDPHAp is a safe and useful bone substitute for OWHTO. MATERIALS AND

methodsSeven patients (2 men and 5 women aged 34-72years) who underwent OWHTO and were followed up for more than 12months were retrospectively studied. After the osteotomy, the gap created was filled with UDPHAp(REGENOS® Kuraray Co.Ltd). Radiography and computed tomography(CT) were performed, and gap healing was assessed postoperatively. The Japanese Orthopaedic Association (JOA) knee score was determined pre- and post-operatively for clinical evaluation.

resultsNeither gross displacement nor collapse of the UDPHAp block graft was observed within 12 months after surgery. Both radiographs and CT showed attenuation of lucency and increasing sclerosis over time. JOA score improved from 71.2 (65-80) to 95.8 (85-100).

conclusionsShort term results for OWHTO using UDPHAp was satisfactory. Clinical improvement of JOA scores were seen, besides osteogenesis was progressing in and around the artificial bone grafts.

Indexed as

AdultAgedBone SubstitutesDurapatiteFemaleHistory, AncientHumansMaleMiddle AgedOsteoarthritis, KneeOsteotomyPorosityRadiographyTibiaTreatment OutcomeBone SubstitutesDurapatite

Identifiers

PMID24997164
PMCPMC4198809

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.