Observational studyThe Journal of pediatrics2014
Maternal obesity, gestational weight gain, and offspring adiposity: the exploring perinatal outcomes among children study.
Observational study in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02304718 (Cycle Study), which is not on this map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cycle Study:an Exercise Intervention to Prevent Gestational Diabetes in Overweight and Obese Chinese Pregnant Women
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 113 citations in OpenAlex.
- Pooled it
- The association between maternal body mass index and child obesity: A systematic review and meta-analysis.PLoS medicine · 2019Pooled it
- Cesarean delivery on maternal request and common child health outcomes: A prospective cohort study in China.Journal of global health · 2022Trial
- Intrauterine DHA exposure and child body composition at 5 y: exploratory analysis of a randomized controlled trial of prenatal DHA supplementation.The American journal of clinical nutrition · 2018Trial
- Associations of Maternal Postpartum Weight Retention and Its Components With Child BMIChildhood obesity (Print) · 2026Article
- Association of Maternal Sociodemographic, Anthropometric, and Lifestyle Factors with Childhood Anthropometric Measures and Anxiety Symptoms: A Nationally Representative Cross-Sectional Study of Preschool-Aged Children in Greece.Diseases (Basel, Switzerland) · 2025Article
- Effects of Infant Formula Type on Early Childhood Growth Outcomes: A Retrospective Cohort Study.Nutrients · 2025Article
- Key questions and gaps in understanding adipose tissue macrophages and early-life metabolic programming.American journal of physiology. Endocrinology and metabolism · 2024Review
- Trimester-specific rate of gestational weight loss or gain and birth size: differences by prepregnancy BMI.Obesity (Silver Spring, Md.) · 2024Article
- The Effect of Prenatal Docosahexaenoic Acid Supplementation on Offspring Fat Mass and Distribution at 24 Months Old.Current developments in nutrition · 2024Article
- Article
- Growth and adiposity in newborns study (GAINS): The influence of prenatal DHA supplementation protocol.Contemporary clinical trials · 2023Article
- Prevalence and pregnant women's knowledge of maternal obesity and excessive gestational weight gain among women attending antenatal care in Fako Division, Cameroon.The Pan African medical journal · 2023Article
- Programming by maternal obesity: a pathway to poor cardiometabolic health in the offspring.The Proceedings of the Nutrition Society · 2022Review
- Morbidity and psychomotor development of offspring of women with gestational diabetes: a 5-year follow-up.BMC pediatrics · 2022Article
- Maternal diet, nutritional status and infant birth weight in Malaysia: a scoping review.BMC pregnancy and childbirth · 2022Article
- Gestational weight change and childhood body composition trajectories from pregnancy to early adolescence.Obesity (Silver Spring, Md.) · 2022Article
- Goals for Reaching Optimal Wellness (GROWell): A clinical trial protocol of a digital dietary intervention for pregnant and postpartum people with prenatal overweight or obesity.Contemporary clinical trials · 2022Article
- Fish oil supplementation of rats fed a high fat diet during pregnancy improves offspring insulin sensitivity.Frontiers in nutrition · 2022Article
- Obesity Impairs Embryonic Myogenesis by Enhancing BMP Signaling within the Dermomyotome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo determine whether adequate vs excessive gestational weight gain (GWG) attenuated the association between maternal obesity and offspring outcomes. STUDY
designData from 313 mother-child pairs participating in the Exploring Perinatal Outcomes among Children study were used to test this hypothesis. Maternal prepregnancy body mass index (BMI) and weight measures throughout pregnancy were abstracted from electronic medical records. GWG was categorized according to the 2009 Institute of Medicine criteria as adequate or excessive. Offspring outcomes were obtained at a research visit (average age 10.4 years) and included BMI, waist circumference (WC), subcutaneous adipose tissue (SAT) and visceral adipose tissue, high-density lipoprotein cholesterol, and triglyceride levels.
resultsMore overweight/obese mothers exceeded the Institute of Medicine GWG recommendations (68%) compared with normal-weight women (50%) (P < .01). Maternal prepregnancy BMI was associated with worse childhood outcomes, particularly among offspring of mothers with excessive GWG (increased BMI [20.34 vs 17.80 kg/m(2)], WC [69.23 vs 62.83 cm], SAT [149.30 vs 90.47 cm(2)], visceral adipose tissue [24.11 vs 17.55 cm(2)], and homeostatic model assessment [52.52 vs 36.69], all P < .001). The effect of maternal prepregnancy BMI on several childhood outcomes was attenuated for offspring of mothers with adequate vs excessive GWG (P < .05 for the interaction between maternal BMI and GWG status on childhood BMI, WC, SAT, and high-density lipoprotein cholesterol).
conclusionOur findings lend support for pregnancy interventions aiming at controlling GWG to prevent childhood obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.