Evidence map›Paper›PMID 24995723›Full record

ReviewBiotechnology journal2014

Preserving human cells for regenerative, reproductive, and transfusion medicine.

Waseem Asghar, Rami El Assal, Hadi Shafiee, Raymond M Anchan, Utkan Demirci

Open access · greenAbstract readReview
In one paragraph

Review in Biotechnology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 95 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. RBC-Derived Optical Nanoparticles Remain Stable After a Freeze-Thaw Cycle.Langmuir : the ACS journal of surfaces and colloids · 2020
    Article
  16. Review
  17. Review
  18. Article
  19. Vitrification and storage of oral mucosa epithelial cell sheets.Journal of tissue engineering and regenerative medicine · 2019
    Article
  20. Technical Considerations in the Freezing, Low-Temperature Storage and Thawing of Stem Cells for Cellular Therapies.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Waseem AsgharBio-Acoustic-MEMS in Medicine (BAMM) Laboratories, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford School of Medicine, Stanford University, Palo Alto, CA, USA.
Rami El Assal
Hadi Shafiee
Raymond M Anchan
Utkan Demirci
Brigham and Women's Hospital · USStanford University · USBluebird Bio (United States) · US

Funding

Minimizing the role of cryoprotectant toxicity for cryopreservationR01EB015776 · NIBIB · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN · 2012 to 2015
$1.5M
Microfluidic Chip for Cryopreservation of Blood CellsR21HL095960 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMIRCI, UTKAN · 2011 to 2012
$491k
Nano-Acoustic Masonry of Microgels for Bottom-Up Tissue EngineeringR21HL112114 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI DEMIRCI, UTKAN, DEMIREL, MELIK · 2012 to 2013
$452k
NHLBI NIH HHS R21 HL095960NHLBI NIH HHS R21-HL095960NHLBI NIH HHS R21 HL112114NIBIB NIH HHS R01 EB015776NIBIB NIH HHS R01-EB015776
6 · The paper itself

Abstract

Cell cryopreservation maintains cellular life at sub-zero temperatures by slowing down biochemical processes. Various cell types are routinely cryopreserved in modern reproductive, regenerative, and transfusion medicine. Current cell cryopreservation methods involve freezing (slow/rapid) or vitrifying cells in the presence of a cryoprotective agent (CPA). Although these methods are clinically utilized, cryo-injury due to ice crystals, osmotic shock, and CPA toxicity cause loss of cell viability and function. Recent approaches using minimum volume vitrification provide alternatives to the conventional cryopreservation methods. Minimum volume vitrification provides ultra-high cooling and rewarming rates that enable preserving cells without ice crystal formation. Herein, we review recent advances in cell cryopreservation technology and provide examples of techniques that are utilized in oocyte, stem cell, and red blood cell cryopreservation.

Indexed as

Cell SurvivalCryopreservationCryoprotective AgentsEmbryonic Stem CellsErythrocytesHumansMesenchymal Stem CellsOocytesRegenerative MedicineReproductive MedicineTransfusion MedicineVitrificationCryoprotective AgentsCryopreservationRegenerative medicineReproductive medicineTransfusion medicineVitrification

Identifiers

PMID24995723
PMCPMC4145864
OpenAlexW2089522209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.