Evidence map›Paper›PMID 24995715›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2014

Disseminated Bacillus Calmette-Guérin (BCG) infection following allogeneic hematopoietic stem cell transplant in a patient with Bare Lymphocyte Syndrome type II.

R F Abu-Arja, B E Gonzalez, M R Jacobs, L Cabral, R Egler, J Auletta, J Arnold, K R Cooke

Open access · greenAbstract readCase Reports
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

R F Abu-ArjaPediatric Bone Marrow Transplant, Nationwide Children's Hospital, Columbus, Ohio, USA.
B E Gonzalez
M R Jacobs
L Cabral
R Egler
J Auletta
J Arnold
K R Cooke
Nationwide Children's Hospital · USRainbow Babies & Children's Hospital · USBoston Children's Hospital · USCleveland Clinic · USJohns Hopkins University · USUniversity Hospitals Case Medical Center · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

We describe the first case, to our knowledge, of disseminated Mycobacterium bovis Bacillus Calmette-Guérin infection in a child with Bare Lymphocyte Syndrome type II after undergoing hematopoietic stem cell transplantation (HSCT). The patient presented 30 days post HSCT with fever and lymphadenitis. Lymph node, blood, and gastric aspirates were positive for M. bovis. The patient received a prolonged treatment course with a combination of isoniazid, levofloxacin, and ethambutol. Her course was further complicated by granulomatous lymphadenitis and otitis media associated with M. bovis that developed during immune suppression taper and immune reconstitution. Ultimately, the patient recovered fully, in association with restoration of immune function, and has completed 12 months of therapy.

Indexed as

Hematopoietic Stem Cell TransplantationMycobacterium bovisBCG VaccineFemaleHumansInfantMycobacterium InfectionsSevere Combined ImmunodeficiencyBCG VaccineBare Lymphocyte Syndrome IIBCG infectionHSCTMycobacterium bovispediatric transplant

Identifiers

PMID24995715
PMCPMC4876699
OpenAlexW1970632478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.