Evidence map›Paper›PMID 24995558›Full record

ReviewCurrent opinion in virology2014

Investigating virus-glycan interactions using glycan microarrays.

David F Smith, Richard D Cummings

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Surface-Controlled Sialoside-Based Biosensing of Viral and Bacterial Neuraminidases.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Glycans in Virus-Host Interactions: A Structural Perspective.Frontiers in molecular biosciences · 2021
    Review
  10. Article
  11. Review
  12. Microbe-focused glycan array screening platform.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  13. Article
  14. Review
  15. Review
  16. O-Glycome Beam Search Arrays for Carbohydrate Ligand Discovery.Molecular & cellular proteomics : MCP · 2018
    Article
  17. Review
  18. Article
  19. Glycan-protein interactions in viral pathogenesis.Current opinion in structural biology · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David F SmithThe National Center for Functional Glycomics, Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, United States.
Richard D CummingsThe National Center for Functional Glycomics, Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, United States. Electronic address: rdcummi@emory.edu.
Emory University · US

Funding

Structural Basis of Immune Recognition of Glycosylated AntigensU54GM062116 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI SASISEKHARAN, RAM · 2001 to 2010
$80.3M
Overall Priority Score P41GM103694 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D · 2013 to 2018
$6.9M
Protein-Glycan Interaction Resource of the CFGR24GM098791 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D, PAULSON, JAMES C · 2011 to 2013
$2.6M
Shotgun Glycomics: Linking Glycan Structure and FunctionR01GM085448 · NIGMS · EMORY UNIVERSITY · PI SMITH, DAVID FLETCHER · 2008 to 2011
$2.3M
NIAID NIH HHS HHSN272201400006CNIGMS NIH HHS P41 GM103694NIGMS NIH HHS P41GM103694NIGMS NIH HHS R01 GM085448NIGMS NIH HHS R01GM085448NIGMS NIH HHS R24 GM098791NIGMS NIH HHS R24GM098791NIGMS NIH HHS U54 GM062116NIGMS NIH HHS U54GM62116
6 · The paper itself

Abstract

While all viruses must transit the plasma membrane of mammalian cells to initiate infection, we know little about the complex processes involved in viral attachment, which commonly involve recognition of glycans by viral proteins. Glycan microarrays derived from both synthetic glycans and natural glycans isolated through shotgun glycomics approaches provide novel platforms for interrogating diverse glycans as potential viral receptors. Recent studies with influenza and rotaviruses using such glycan microarrays provide examples of their utility in exploring the challenging questions raised in efforts to define the complex mechanistic protein-glycan interactions that regulate virus attachment to host cells.

Indexed as

Microarray AnalysisAnimalsGlycomicsHumansInfluenza, HumanPolysaccharidesReceptors, VirusRotavirusRotavirus InfectionsPolysaccharidesReceptors, Virus

Identifiers

PMID24995558
PMCPMC4149940
OpenAlexW2069669384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.