ArticleJournal of ophthalmic inflammation and infection2014
A case of bilateral human herpes virus 6 panuveitis with genomic viral DNA integration.
Article in Journal of ophthalmic inflammation and infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient.Journal of ophthalmic inflammation and infection · 2025Article
- HHV-6B- and HHV-7-associated choroiditis secondary to acute myelogenous leukemia: a case report.The Journal of international medical research · 2023Article
- Long-term outcome in corneal endotheliitis with molecular detection of herpes simplex virus 1 and human herpes virus 6: a case report.BMC ophthalmology · 2022Article
- Human Herpesvirus-6 corneal Endotheliitis after intravitreal injection of Ranibizumab.BMC ophthalmology · 2019Article
- Delayed bilateral fibrinous anterior chamber reaction following autologous bone marrow transplant and cataract surgery.American journal of ophthalmology case reports · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundWe report a rare case of bilateral panuveitis from human herpes virus 6 (HHV-6) with genomic viral DNA integration in an immunocompromised man.
findingsA 59-year-old man with history of multiple myeloma presented with altered mental status, bilateral eye redness, and blurry vision. Examination revealed bilateral diffuse keratic precipitates, 4+ anterior chamber cell, hypopyon, vitritis, and intraretinal hemorrhages. Intraocular fluid testing by polymerase chain reaction (PCR) was positive for HHV-6. The patient was successfully treated with intravitreal foscarnet and intravenous ganciclovir and foscarnet. Despite clinical improvement, his serum HHV-6 levels remained high, and it was concluded that he had HHV-6 chromosomal integration.
conclusionsHHV-6 should be considered in the differential for infectious uveitis in immunocompromised hosts who may otherwise have a negative work-up. HHV-6 DNA integration may lead to difficulties in disease diagnosis and determining disease resolution.
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