Evidence map›Paper›PMID 24994847›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2015

Association between the Mediterranean diet and cognitive decline in a biracial population.

Alain Koyama, Denise K Houston, Eleanor M Simonsick, Jung Sun Lee, Hilsa N Ayonayon, Danit R Shahar, Caterina Rosano, Suzanne Satterfield, Kristine Yaffe

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 6 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
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  7. Article
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  11. Association of MIND diet with cognitive decline among Black and White older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  12. Article
  13. The Health, Aging, and Body Composition (Health ABC) Study-Ground-Breaking Science for 25 Years and Counting.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
  14. Review
  15. Article
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  19. Unhealthy foods may attenuate the beneficial relation of a Mediterranean diet to cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Alain KoyamaNorthern California Institute For Research and Education, San Francisco. San Francisco VA Medical Center, California. akk412@mail.harvard.edu.
Denise K HoustonSticht Center on Aging, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Eleanor M SimonsickIntramural Research Program, National Institute on Aging, Baltimore, Maryland.
Jung Sun LeeUniversity of Georgia, Athens.
Hilsa N AyonayonDepartment of Epidemiology and Biostatistics, University of California San Francisco.
Danit R ShaharS. Daniel International Center for Health and Nutrition, Department of Epidemiology and Health Evaluation, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel.
Caterina RosanoGraduate School of Public Health, University of Pittsburgh, Pennsylvania.
Suzanne SatterfieldUniversity of Tennessee Health Science Center, Memphis.
Kristine YaffeSan Francisco VA Medical Center, California. Department of Epidemiology and Biostatistics, University of California San Francisco. Departments of Psychiatry and Neurology, University of California San Francisco.
San Francisco VA Medical Center · USNational Institute on Aging · USUniversity of California, San Francisco · USUniversity of Georgia · USUniversity of Pittsburgh · USUniversity of Tennessee Health Science Center · USWake Forest University · US

Funding

Changes in Sleep and Cognition in Older WomenR01AG026720 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STONE, KATIE L, YAFFE, KRISTINE · 2006 to 2016
$7.5M
Peripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
Predictors & Outcomes of Cognitive Trajectories in the Oldest OldK24AG031155 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAFFE, KRISTINE · 2007 to 2020
$1.5M
DYNAMICS OF HEALTH .AGING . AND BODY COMPOSITION /Pittsburgh/-260962101N01AG062101 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1996 to 2004
$996k
DYNAMICS OF HEALTH . AGING . AND BODY COMPOSITION /Memphis/-26062103N01AG062103 · NIA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 1996 to 2004
$793k
HEALTH ABC--COORDINATING UNIT /California/-260062106N01AG062106 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 1996 to 2004
$109k
Intramural NIH HHSNIA NIH HHS K24 AG 031155NIA NIH HHS K24 AG031155NIA NIH HHS N01-AG-6-2101NIA NIH HHS N01-AG-6-2103NIA NIH HHS N01-AG-6-2106NIA NIH HHS R01 AG 026720NIA NIH HHS R01 AG026720NIA NIH HHS R01 AG028050NIA NIH HHS R01-AG028050NINR NIH HHS R01 NR012459NINR NIH HHS R01-NR012459
6 · The paper itself

Abstract

backgroundResults from numerous studies suggest protective effects of the Mediterranean diet for cardiovascular disease, cancer, and mortality. Evidence for an association with a decreased risk of cognitive decline is less consistent and studies are limited by a lack of diversity in their populations.

methodsWe followed 2,326 older adults (38.2% black, 51.3% female, aged 70-79 at baseline) over 8 years in a prospective cohort study in the United States (Health, Aging and Body Composition study). To measure adherence to a Mediterranean diet, we calculated race-specific tertiles of the MedDiet score (range: 0-55) using baseline food frequency questionnaires. Cognitive decline was assessed using repeated Modified Mini Mental State Examination scores over the study. We used linear mixed models to assess the association between MedDiet score and trajectory of cognitive decline.

resultsAmong blacks, participants with high MedDiet scores had a significantly lower mean rate of decline on the Modified Mini Mental State Examination score compared with participants with lower MedDiet scores (middle and bottom tertiles). The mean difference in points per year was 0.22 (95% confidence interval: 0.05-0.39; p = .01) after adjustment for age, sex, education, body mass index, current smoking, physical activity, depression, diabetes, total energy intake, and socioeconomic status. No association between MedDiet scores and change in Modified Mini Mental State Examination score was seen among white participants (p = .14).

conclusionsStronger adherence to the Mediterranean diet may reduce the rate of cognitive decline among black, but not white older adults. Further studies in diverse populations are needed to confirm this association and pinpoint mechanisms that may explain these results.

Indexed as

AgedBlack or African AmericanCognition DisordersCohort StudiesDiet, MediterraneanFemaleHealth BehaviorHumansLife StyleMaleSocioeconomic FactorsUnited StatesWhite PeopleAlzheimersCognition.Cognitive agingEpidemiologyNutrition

Identifiers

PMID24994847
PMCPMC4351391
OpenAlexW2113036039

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.