ArticleNature communications2014
Substrate-water exchange in photosystem II is arrested before dioxygen formation.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 91 citations in OpenAlex.
- New Water Oxidation Mechanism in Photosystem II Resolves Major Experimental Controversies.Angewandte Chemie (International ed. in English) · 2026Article
- Time-resolved Mn KThe Journal of biological chemistry · 2026Article
- Self-assembled [2 + 3] organic-imine cage as an artificial light harvester for the photocatalytic organic transformation in an aqueous medium.RSC advances · 2025Article
- Insights from CaPhotosynthesis research · 2024Review
- On the simulation and interpretation of substrate-water exchange experiments in photosynthetic water oxidation.Photosynthesis research · 2024Article
- Theoretical elucidation of the structure, bonding, and reactivity of the CaMnPhotosynthesis research · 2024Review
- Unravelling MnPhysical chemistry chemical physics : PCCP · 2024Article
- Assignment of the slowly exchanging substrate water of nature's water-splitting cofactor.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Review
- Genome-Wide Identification and Expression Analyses of theCurrent issues in molecular biology · 2024Article
- Solar energy conversion by photosystem II: principles and structures.Photosynthesis research · 2023Review
- Coemissive luminescent nanoparticles combining aggregation-induced emission and quenching dyes prepared in continuous flow.Nature communications · 2022Article
- Reversible Structural Isomerization of Nature's Water Oxidation Catalyst Prior to O-O Bond Formation.Journal of the American Chemical Society · 2022Article
- From manganese oxidation to water oxidation: assembly and evolution of the water-splitting complex in photosystem II.Photosynthesis research · 2022Review
- The exchange of the fast substrate water in the SChemical science · 2021Article
- Water oxidation in photosystem II.Photosynthesis research · 2019Review
- Interaction of methanol with the oxygen-evolving complex: atomistic models, channel identification, species dependence, and mechanistic implications.Chemical science · 2016Article
- Structural rearrangements preceding dioxygen formation by the water oxidation complex of photosystem II.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Rapid evolution of the Photosystem II electronic structure during water splitting.Physical review. XArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light-driven oxidation of water into dioxygen, catalysed by the oxygen-evolving complex (OEC) in photosystem II, is essential for life on Earth and provides the blueprint for devices for producing fuel from sunlight. Although the structure of the OEC is known at atomic level for its dark-stable state, the mechanism by which water is oxidized remains unsettled. Important mechanistic information was gained in the past two decades by mass spectrometric studies of the H2(18)O/H2(16)O substrate-water exchange in the four (semi) stable redox states of the OEC. However, until now such data were not attainable in the transient states formed immediately before the O-O bond formation. Using modified photosystem II complexes displaying up to 40-fold slower O2 production rates, we show here that in the transient S3YZ state the substrate-water exchange is dramatically slowed as compared with the earlier S states. This further constrains the possible sites for substrate-water binding in photosystem II.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.