Evidence map›Paper›PMID 24993561›Full record

Trial reportContemporary clinical trials2014

Mindfulness-based intervention for prodromal sleep disturbances in older adults: design and methodology of a randomized controlled trial.

David S Black, Gillian A O'Reilly, Richard Olmstead, Elizabeth C Breen, Michael R Irwin

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02977988 (Neural Mechanisms in Women's Treatment and Early Recovery), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02977988 nacompletednot on this mapstarted 2015, after this paper: background citation

Neural Mechanisms in Women's Treatment and Early Recovery

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2015 to 2019Enrolled200ConditionsSubstance-related DisordersArmsMindfulness Meditation, Brain and Recovery (B&R)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. The Effect of Mind-Body Therapies on Insomnia: A Systematic Review and Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

David S BlackDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA. Electronic address: davidbla@usc.edu.
Gillian A O'ReillyDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Richard OlmsteadCousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, USA.
Elizabeth C BreenCousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, USA.
Michael R IrwinCousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, USA.

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOORE, ALISON AHERN · 2006 to 2017
$9.8M
Training grant for Cancer Control and EpidemiologyT32CA009492 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN · 1985 to 2019
$7.4M
Aging: Sleep and Inflammatory Mechanisms in Depression PreventionR01AG026364 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2005 to 2015
$5.8M
Sleep, Inflamation, and Depression Occurrence in Breast Cancer SurvivorsR01CA160245 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2012 to 2016
$3.9M
Chronic Moderate Sleep Restriction in Older Long and Older Average SleepersR01HL095799 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI IRWIN, MICHAEL R, JEAN-LOUIS, GIRARDIN · 2011 to 2015
$3.8M
Mechanisms of Sleep Disruption HyperalgesiaR01DA032922 · NIDA · JOHNS HOPKINS UNIVERSITY · PI IRWIN, MICHAEL R, SMITH, MICHAEL T · 2012 to 2016
$2.7M
Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune MechanismsR01CA119159 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2006 to 2010
$2.2M
Subjective Social Isolation and Sleep Disturbances: Inflammatory Mechanisms in AgR01AG034588 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 2009 to 2013
$1.9M
Post-Graduate Training Program in Psychoneuroimmunology and Mental HealthT32MH019925 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRWIN, MICHAEL R · 1997 to 2012
$1.7M
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NCI NIH HHS R01 CA119159NCI NIH HHS R01-CA119159NCI NIH HHS R01 CA160245NCI NIH HHS R01 CA160245-01NCI NIH HHS T32CA009492NHLBI NIH HHS R01 HL095799NHLBI NIH HHS R01HL095799NIA NIH HHS AG028748NIA NIH HHS P30 AG028748NIA NIH HHS P30-AG028748NIA NIH HHS R01 AG026364NIA NIH HHS R01-AG026364NIA NIH HHS R01 AG034588NIA NIH HHS R01-AG034588NIDA NIH HHS R01 DA032922NIDA NIH HHS R01 DA032922-01NIMH NIH HHS 5T32-MH019925NIMH NIH HHS T32 MH019925
6 · The paper itself

Abstract

Sleep problems are prevalent among older adults, often persist untreated, and are predictive of health detriments. Given the limitations of conventional treatments, non-pharmacological treatments such as mindfulness-based interventions (MBIs) are gaining popularity for sleep ailments. However, nothing is yet known about the impact of MBIs on sleep in older adults with prodromal sleep disturbances. This article details the design and methodology of a 6-week parallel-group RCT calibrated to test the treatment effect of the Mindful Awareness Practices (MAPs) program versus sleep hygiene education for improving sleep quality, as the main outcome, in older adults with prodromal sleep disturbances. Older adults with current sleep disturbances will be recruited from the urban Los Angeles community. Participants will be randomized into two standardized treatment conditions, MAPs and sleep hygiene education. Each condition will consist of weekly 2-hour group-based classes over the course of the 6-week intervention. The primary objective of this study is to determine if mindfulness meditation practice as engaged through the MAPs program leads to improved sleep quality relative to sleep hygiene education in older adults with prodromal sleep disturbances.

Indexed as

AgingProdromal SymptomsAgedAged, 80 and overFemaleHealth BehaviorHumansLos AngelesMaleMeditationMiddle AgedMindfulnessPatient Education as TopicQuality of LifeResearch DesignSleep Wake DisordersDesign and methodologyInflammatory markersMindfulnessOlder adultsRandomized controlled trialSleep problems

Identifiers

PMID24993561
PMCPMC4175059

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.