Why isn't endogenous ouabain more widely accepted?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. An Introduction to Spiral Steroids.International journal of molecular sciences · 2022
   Review
2. Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases.International journal of molecular sciences · 2018
   Review
3. Digoxin, an Overlooked Agonist of RORγ/RORγT.Frontiers in pharmacology · 2018
   Article
4. The pump, the exchanger, and the holy spirit: origins and 40-year evolution of ideas about the ouabain-NaAmerican journal of physiology. Cell physiology · 2018
   Review
5. Comparison of Digitalis Sensitivities of NaACS omega · 2017
   Article
6. Sodium potassium adenosine triphosphatase (Na/K-ATPase) as a therapeutic target for uremic cardiomyopathy.Expert opinion on therapeutic targets · 2017
   Review
7. Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress.Antioxidants (Basel, Switzerland) · 2017
   Review
8. Regulation of Cardiac Remodeling by Cardiac Na(+)/K(+)-ATPase Isoforms.Frontiers in physiology · 2016
   Review
9. Molecular Properties of Globin Channels and Pores: Role of Cholesterol in Ligand Binding and Movement.Frontiers in physiology · 2016
   Article
10. Na+/Ca2+ exchange and Na+/K+-ATPase in the heart.The Journal of physiology · 2015
    Review
11. The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease.Frontiers in pharmacology · 2015
    Review
12. Editorial: Natriuretic Hormones.Frontiers in endocrinology · 2015
    Article
13. Endogenous digitalis-like factors: an overview of the history.Frontiers in endocrinology · 2015
    Review
14. Evidence for a 12 kDa "Carrier Protein" for Natriuretic Hormone.Frontiers in endocrinology · 2014
    Review
15. A New Animal Model to Study Endogenous Cardiotonic Steroids and the Progression of Cardiovascular Events in Salt-Sensitive Hypertension.International archives of translational medicine
    Article

Corrections and comments

• Commented on by
  Letter to the editor: "Why isn't clinical experience with ouabain more widely accepted?".2014
• Commented on by
  Reply to "Letter to the editor: 'Why isn't clinical experience with ouabain more widely accepted?'".2014

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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