Evidence map›Paper›PMID 24993038›Full record

ArticleHead and neck pathology2015

Rhabdoid Variant of Myoepithelial Carcinoma, with EWSR1 Rearrangement: Expanding the Spectrum of EWSR1-Rearranged Myoepithelial Tumors.

Khin Thway, Nick Bown, Aisha Miah, Rob Turner, Cyril Fisher

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. SWI/SNF complex-deficient soft tissue neoplasms: An update.Seminars in diagnostic pathology · 2021
    Review
  4. Article
  5. Review
  6. Article
  7. What is new in epithelioid soft tissue tumors?Virchows Archiv : an international journal of pathology · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Khin ThwaySarcoma Unit, Royal Marsden Hospital, London, UK, khin.thway@rmh.nhs.uk.
Nick Bown
Aisha Miah
Rob Turner
Cyril Fisher
Royal Marsden Hospital · GBSt James's University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myoepithelial and mixed tumors represent a heterogeneous group of neoplasms for which classification is incomplete and continues to evolve. Those arising in the soft tissues appear to represent subgroups that are genetically distinct from those that occur within salivary glands. We describe a case of soft tissue myoepithelial carcinoma with rhabdoid morphology, which presented as an enlarging neck mass in a 40 year old male, and in which EWSR1 rearrangement was demonstrated by fluorescence in situ hybridization. This neoplasm showed diffuse INI1 loss, making distinction from other INI1-negative rhabdoid tumors difficult. This expands the range of reported histologic features of EWSR1-rearranged myoepithelial neoplasms, and highlights the significant morphologic and immunohistochemical overlap between this and other INI1-negative malignant rhabdoid neoplasms.

Indexed as

AdultBiomarkers, TumorCalmodulin-Binding ProteinsChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDNA, NeoplasmGene RearrangementHumansMaleMyoepitheliomaNeckRhabdoid TumorRNA-Binding Protein EWSRNA-Binding ProteinsSMARCB1 ProteinSoft Tissue NeoplasmsBiomarkers, TumorCalmodulin-Binding ProteinsChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDNA, NeoplasmEWSR1 protein, humanRNA-Binding Protein EWSRNA-Binding ProteinsSMARCB1 ProteinSMARCB1 protein, humanTranscription Factors

Identifiers

PMID24993038
PMCPMC4424215
OpenAlexW2063177330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.