ArticleInternational journal of environmental research and public health2014
Multilevel analysis of air pollution and early childhood neurobehavioral development.
Article in International journal of environmental research and public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Effects of prenatal exposure to NOEnvironmental science and pollution research international · 2020Pooled it
- Air pollution mixtures and cognitive outcomes in children: associations with school-age exposure and sex differences.European journal of pediatrics · 2026Article
- Urban-rural heterogeneity in the association of indoor air pollution exposure with early childhood development among children aged 0-5 years in a Chinese plateau area.BMC public health · 2025Article
- Assessing the association between household air pollution exposure and child heath in Mongolia: a birth-cohort study.Scientific reports · 2025Article
- Article
- Pre-pregnancy ozone and ultrafine particulate matter exposure during second year of life associated with decreased cognitive and adaptive functioning at aged 2-5 years.Environmental research · 2024Article
- Indoor air pollution exposure and early childhood development in the Upstate KIDS Study.Environmental research · 2023Article
- Impacts of Indoor Dust Exposure on Human Colonic Cell Viability, Cytotoxicity and Apoptosis.Toxics · 2023Article
- The Effect of Maternal Exposure to Air Pollutants and Heavy Metals during Pregnancy on the Risk of Neurological Disorders Using the National Health Insurance Claims Data of South Korea.Medicina (Kaunas, Lithuania) · 2023Article
- DNA methylation is associated with prenatal exposure to sulfur dioxide and childhood attention-deficit hyperactivity disorder symptoms.Scientific reports · 2023Article
- Air Pollution-Related Neurotoxicity Across the Life Span.Annual review of pharmacology and toxicology · 2023Review
- Article
- Associations of Pre- and Postnatal Air Pollution Exposures with Child Behavioral Problems and Cognitive Performance: A U.S. Multi-Cohort Study.Environmental health perspectives · 2022Article
- Early life exposure to residential green space impacts cognitive functioning in children aged 4 to 6 years.Environment international · 2022Article
- Air Pollution during Pregnancy and Childhood Autism Spectrum Disorder in Taiwan.International journal of environmental research and public health · 2021Article
- Prenatal air pollution exposure and neurodevelopment: A review and blueprint for a harmonized approach within ECHO.Environmental research · 2021Review
- Running and Physical Activity in an Air-Polluted Environment: The Biomechanical and Musculoskeletal Protocol for a Prospective Cohort Study 4HAIE (Healthy Aging in Industrial Environment-Program 4).International journal of environmental research and public health · 2020Article
- Outdoor air pollution pregnancy exposures are associated with behavioral problems in China's preschoolers.Environmental science and pollution research international · 2019Article
- The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease - Evidence from epidemiological and animal studies.Biomedical journal · 2018Review
- Pollution from Fossil-Fuel Combustion is the Leading Environmental Threat to Global Pediatric Health and Equity: Solutions Exist.International journal of environmental research and public health · 2017Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the association between the ambient air pollution levels during the prenatal and postnatal stages and early childhood neurobehavioral development, our study recruited 533 mother-infant pairs from 11 towns in Taiwan. All study subjects were asked to complete childhood neurobehavioral development scales and questionnaires at 6 and 18 months. Air pollution, including particulate matter ≤10 μm (PM10), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), and hydrocarbons, was measured at air quality monitoring stations in the towns where the subjects lived. Multilevel analyses were applied to assess the association between air pollution and childhood neurobehavioral development during pregnancy and when the children were 0 to 6 months, 7 to 12 months, and 13 to 18 months old. At 18 months, poor subclinical neurodevelopment in early childhood is associated with the average SO2 exposure of prenatal, during all trimesters of pregnancy and at postnatal ages up to 12 months (first trimester β = -0.083, se = 0.030; second and third trimester β = -0.114, se = 0.045; from birth to 12 months of age β = -0.091, se = 0.034). Furthermore, adverse gross motor below average scores at six months of age were associated with increased average non-methane hydrocarbon, (NMHC) levels during the second and third trimesters (β = -8.742, se = 3.512). Low-level SO2 exposure prenatally and up to twelve months postnatal could cause adverse neurobehavioral effects at 18 months of age. Maternal NMHC exposure during the 2nd and 3rd trimesters of pregnancy would be also associated with poor gross motor development in their children at 6 months of age.
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