Evidence map›Paper›PMID 24992241›Full record

ArticleBiomacromolecules2014

Synthetic oral mucin mimic from polymer micelle networks.

Sundar P Authimoolam, Andrew L Vasilakes, Nihar M Shah, David A Puleo, Thomas D Dziubla

Abstract read
In one paragraph

Article in Biomacromolecules, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Mucus-Inspired Dynamic Hydrogels: Synthesis and Future Perspectives.Journal of the American Chemical Society · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sundar P AuthimoolamDepartment of Chemical and Materials Engineering, College of Engineering, University of Kentucky , 177 F. Paul Anderson Tower, Lexington, Kentucky 40506, United States.
Andrew L Vasilakes
Nihar M Shah
David A Puleo
Thomas D Dziubla
University of Kentucky · US

Funding

Enhanced Oral Tissue Repair via Self Assembled Polymer Multi-layer Barriers for tR03DE019496 · NIDCR · UNIVERSITY OF KENTUCKY · PI DZIUBLA, THOMAS DEAN · 2009 to 2010
$221k
NIDCR NIH HHS R03 DE019496
6 · The paper itself

Abstract

Mucin networks are formed in the oral cavity by complexation of glycoproteins with other salivary proteins, yielding a hydrated lubricating barrier. The function of these networks is linked to their structural, chemical, and mechanical properties. Yet, as these properties are interdependent, it is difficult to tease out their relative importance. Here, we demonstrate the ability to recreate the fibrous like network through a series of complementary rinses of polymeric worm-like micelles, resulting in a 3-dimensional (3D) porous network that can be deposited layer-by-layer onto any surface. In this work, stability, structure, and microbial capture capabilities were evaluated as a function of network properties. It was found that network structure alone was sufficient for bacterial capture, even with networks composed of the adhesion-resistant polymer, poly(ethylene glycol). The synthetic networks provide an excellent, yet simple, means of independently characterizing mucin network properties (e.g., surface chemistry, stiffness, and pore size).

Indexed as

MicellesBiomimeticsCurcuminMicrobial Sensitivity TestsMicroscopy, Electron, ScanningMucinsPolyethylene GlycolsPolymersPorosityStaphylococcus aureusStreptavidinCurcuminMicellesMucinsPolyethylene GlycolsPolymersStreptavidin

Identifiers

PMID24992241
PMCPMC4130247
OpenAlexW2014056132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.