Evidence map›Paper›PMID 24991964›Full record

Trial reportNeuron2014

Intrinsic and task-evoked network architectures of the human brain.

Michael W Cole, Danielle S Bassett, Jonathan D Power, Todd S Braver, Steven E Petersen

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Neuron, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 929 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
929citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

929 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Network-oriented neurorehabilitation after stroke: a paradigmatic approach.Journal of neuroengineering and rehabilitation · 2026
    Review
  7. Human cerebral cortex organization characterized by functional PET-FDG "Metabolic Connectivity".European journal of nuclear medicine and molecular imaging · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Functional brain organization is stable within individuals across years.bioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

869 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael W ColeCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA; Department of Psychology, Washington University, St. Louis, MO 63130, USA. Electronic address: michael.cole@rutgers.edu.
Danielle S BassettDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jonathan D PowerDepartment of Neurology, Washington University, St. Louis, MO 63110, USA.
Todd S BraverDepartment of Psychology, Washington University, St. Louis, MO 63130, USA.
Steven E PetersenDepartment of Psychology, Washington University, St. Louis, MO 63130, USA; Department of Neurology, Washington University, St. Louis, MO 63110, USA.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Network Mechanisms of Flexible Cognitive ControlR00MH096801 · NIMH · RUTGERS THE STATE UNIV OF NJ NEWARK · PI COLE, MICHAEL WILLIAM · 2014 to 2016
$747k
Network Mechanisms of Flexible Cognitive ControlK99MH096801 · NIMH · WASHINGTON UNIVERSITY · PI COLE, MICHAEL WILLIAM · 2012 to 2013
$165k
NIMH NIH HHS 1U54MH091657NIMH NIH HHS K99 MH096801NIMH NIH HHS K99/R00 MH096801NIMH NIH HHS R00 MH096801NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Many functional network properties of the human brain have been identified during rest and task states, yet it remains unclear how the two relate. We identified a whole-brain network architecture present across dozens of task states that was highly similar to the resting-state network architecture. The most frequent functional connectivity strengths across tasks closely matched the strengths observed at rest, suggesting this is an "intrinsic," standard architecture of functional brain organization. Furthermore, a set of small but consistent changes common across tasks suggests the existence of a task-general network architecture distinguishing task states from rest. These results indicate the brain's functional network architecture during task performance is shaped primarily by an intrinsic network architecture that is also present during rest, and secondarily by evoked task-general and task-specific network changes. This establishes a strong relationship between resting-state functional connectivity and task-evoked functional connectivity-areas of neuroscientific inquiry typically considered separately.

Indexed as

AdultBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNerve NetPsychomotor PerformanceRestYoung Adult

Identifiers

PMID24991964
PMCPMC4082806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.