ArticleSurgical neurology international2014
Acanthamoeba encephalitis: A Case Report and Review of Therapy.
Article in Surgical neurology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Comprehensive characterization of extracellular vesicles produced by environmental (Neff) and clinical (T4) strains ofmSystems · 2024Article
- Acanthamoeba castellanii encephalitis in a patient with AIDS: a case report and literature review.The Lancet. Infectious diseases · 2022Review
- Case Report: First Successful Treatment of Acanthamoeba Brain Abscess with Combination Surgical Excision and Miltefosine-Led Antimicrobial Therapy.The American journal of tropical medicine and hygiene · 2022Review
- Detection of Acanthamoeba spp. using carboxylesterase antibody and its usage for diagnosing Acanthamoeba-keratitis.PloS one · 2022Article
- Review
- Immunopathogenicity ofInternational journal of molecular sciences · 2021Review
- Minimal Cerebrospinal Fluid Concentration of Miltefosine despite Therapeutic Plasma Levels during the Treatment of Amebic Encephalitis.Antimicrobial agents and chemotherapy · 2019Article
- Acanthamoeba in Southeast Asia - Overview and Challenges.The Korean journal of parasitology · 2019Review
- Isolation, identification of pathogenicJournal of advanced veterinary and animal research · 2018Article
- Non-granulomatous cerebellar infection by Acanthamoeba spp. in an immunocompetent host.Infection · 2018Article
- Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts.Parasites & vectors · 2018Article
- An Unusual Cause of Central Nervous System Infection During Acute Myeloid Leukemia Induction Chemotherapy:Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2018Article
- Disseminated Acanthamoeba infection in a heart transplant recipient treated successfully with a miltefosine-containing regimen: Case report and review of the literature.Transplant infectious disease : an official journal of the Transplantation Society · 2017Review
- Artemisinin and its derivatives in treating protozoan infections beyond malaria.Pharmacological research · 2017Review
- Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report.Open forum infectious diseases · 2015Article
- Fatal acanthamoeba encephalitis in a patient with a total artificial heart (syncardia) device.Open forum infectious diseases · 2014Article
- Twenty years of acanthamoeba diagnostics in Austria.The Journal of eukaryotic microbiologyReview
- Granulomatous Amebic Encephalitis Presenting Like a Tumor-Chasing a Diagnostic Conundrum.Annals of Indian Academy of NeurologyArticle
- Something Amiss: Acanthamoeba Meningoencephalitis: Report of Two Cases from Kolkata, India.Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcanthamoeba is a rare cause of encephalitis yet is associated with high mortality. Treatment protocols vary greatly and generally include combination therapy across a wide spectrum of antiinfective classes. CASE DESCRIPTION: A 63-year-old male who underwent renal transplantation presented 6 months after transplantation with depressed level of consciousness. Imaging of the head with computerized tomography showed an enhancing lesion suspicious for brain abscess. Biopsy of the lesion showed Acanthamoeba cysts. The patient was treated with sulfadiazine, fluconazole, flucytosine, azithromycin, and miltefosine but without success. We review recently published cases of Acanthamoeba encephalitis with an emphasis on treatment protocols and outcomes.
conclusionFree-living protozoans such as Acanthamoeba are ubiquitous in the environment and should be suspected in immunosuppressed persons who present with central nervous system findings and brain abscess. Biopsy is critical to establish the etiology so that appropriate combination therapy can be deployed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.