ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Aversive prediction error signals in the amygdala.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 72 citations in OpenAlex.
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- Irrelevant Threats Linger and Affect Behavior in High Anxiety.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
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- The Roles of Basolateral Amygdala Parvalbumin Neurons in Fear Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Retrorubral field is a hub for diverse threat and aversive outcome signals.Current biology : CB · 2021Article
- Neural substrates of appetitive and aversive prediction error.Neuroscience and biobehavioral reviews · 2021Review
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- Neural Computations of Threat.Trends in cognitive sciences · 2021Review
- The Aversion Function of the Limbic Dopaminergic Neurons and Their Roles in Functional Neurological Disorders.Frontiers in cell and developmental biology · 2021Review
- Approach-Avoidance Decisions Under Threat: The Role of Autonomic Psychophysiological States.Frontiers in neuroscience · 2021Article
- The influence of subcortical shortcuts on disordered sensory and cognitive processing.Nature reviews. Neuroscience · 2020Review
- Distinct Processing of Aversive Experience in Amygdala Subregions.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Article
- Between placebo and nocebo: Response to control treatment is mediated by amygdala activity and connectivity.European journal of pain (London, England) · 2020Article
- Potential Neural Mediators of Mom Power Parenting Intervention Effects on Maternal Intersubjectivity and Stress Resilience.Frontiers in psychiatry · 2020Article
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- Boundary effects of expectation in human pain perception.Scientific reports · 2019Article
- Enhanced discriminative aversive learning and amygdala responsivity in 5-HT transporter mutant mice.Translational psychiatry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Prediction error signals are fundamental to learning. Here, in mice, we show that aversive prediction signals are found in the hemodynamic responses and theta oscillations recorded from the basolateral amygdala. During fear conditioning, amygdala responses evoked by footshock progressively decreased, whereas responses evoked by the auditory cue that predicted footshock concomitantly increased. Unexpected footshock evoked larger amygdala responses than expected footshock. The magnitude of the amygdala response to the footshock predicted behavioral responses the following day. The omission of expected footshock led to a decrease below baseline in the amygdala response suggesting a negative aversive prediction error signal. Thus, in mice, amygdala activity conforms to temporal difference models of aversive learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.