ArticleBlood2014
Platelet diameters in inherited thrombocytopenias: analysis of 376 patients with all known disorders.
Article in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 143 citations in OpenAlex.
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- A proactive large platelet-driven screening strategy for the early recognition of MYH9-related disease: a Chinese prospective cohort study.Research and practice in thrombosis and haemostasis · 2026Article
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- Expanded clinical, genetic, and biological spectrum of filaminopathies with hematological involvement.Haematologica · 2026Article
- Platelet Adhesion and Aggregation Dynamics over Collagen- and VWF-coated Surfaces: Insights from Dissipative Particle Dynamics Simulations and Microfluidic Experiments.Bulletin of mathematical biology · 2026Article
- Clinical and Molecular Spectrum of MYH9-Thrombocytopenia: Insights from a Single Centric Pediatric Cohort.Children (Basel, Switzerland) · 2025Article
- Characterization of a novelHaematologica · 2025Article
- Pseudothrombocytopenia and other conditions associated with spuriously low platelet counts.Haematologica · 2025Review
- Isolation Techniques of Micro/Nano-Scaled Species for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Thrombocytopenia, renal failure and hearing loss in a young patient:BMJ case reports · 2025Article
- Diagnosis of Inherited Platelet Disorders: Clinical Evaluation and Functional and Molecular Assays.Biomolecules · 2025Review
- [Clinical characteristics and treatment outcomes of adult patients with phytosterolemia presenting with Thrombocytopenia].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2025Article
- Looking Under the Hood at the Cytoskeletal Engine of Platelet Production.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Acquired platelet disorders.Frontiers in medicine · 2025Review
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- A New Shear-Stress-Based Point-of-Care Technology for Evaluation of the Hemostatic Pattern in Whole Blood.Biosensors · 2024Article
- Improving the hemocompatibility of a porohyperelastic layered vascular graft using luminal reversal microflows.Journal of the mechanical behavior of biomedical materials · 2024Article
- Review
- Bioprinting Soft 3D Models of Hematopoiesis using Natural Silk Fibroin-Based Bioink Efficiently Supports Platelet Differentiation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Case Report:Frontiers in pediatrics · 2024Article
Corrections and comments
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Authors and funding
23 authors at 16 institutions in 5 countries.
Funding
Abstract
Abnormalities of platelet size are one of the distinguishing features of inherited thrombocytopenias (ITs), and evaluation of blood films is recommended as an essential step for differential diagnosis of these disorders. Nevertheless, what we presently know about this subject is derived mainly from anecdotal evidence. To improve knowledge in this field, we evaluated platelet size on blood films obtained from 376 patients with all 19 forms of IT identified so far and found that these conditions differ not only in mean platelet diameter, but also in platelet diameter distribution width and the percentage of platelets with increased or reduced diameters. On the basis of these findings, we propose a new classification of ITs according to platelet size. It distinguishes forms with giant platelets, with large platelets, with normal or slightly increased platelet size, and with normal or slightly decreased platelet size. We also measured platelet diameters in 87 patients with immune thrombocytopenia and identified cutoff values for mean platelet diameter and the percentage of platelets with increased or reduced size that have good diagnostic accuracy in differentiating ITs with giant platelets and with normal or slightly decreased platelet size from immune thrombocytopenia and all other forms of IT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.