Evidence map›Paper›PMID 24990475›Full record

ArticleInternational journal of epidemiology2015

Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador.

Philip J Cooper, Martha E Chico, Thomas Ae Platts-Mills, Laura C Rodrigues, David P Strachan, Mauricio L Barreto

Abstract read
In one paragraph

Article in International journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Philip J CooperLaboratorio de Investigaciones FEPIS, Quinindé, Esmeraldas Province, Ecuador, Institute of Infection and Immunity Research, Institute of Population Health Research, St George's University of London, London, UK, Centro de Investigación en Enfermedades Infecciosas, Escuela de Biología, Pontificia Universidad Católica del Ecuador, Quito, Ecuador, pcooper@sgul.ac.uk.
Martha E ChicoLaboratorio de Investigaciones FEPIS, Quinindé, Esmeraldas Province, Ecuador.
Thomas Ae Platts-MillsDivision of Allergy and Clinical Immunology, University of Virginia Health System, Charlottesville, VA, USA.
Laura C RodriguesInfectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, London, UK and.
David P StrachanInstitute of Population Health Research, St George's University of London, London, UK.
Mauricio L BarretoInstituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil.

Funding

IgE antibodies to the mammalian oligosaccharide galactose-alpha-1, 3-galactose (alpha-gal): immunology, epidemiology and relevance to allergic and inflammatory diseaseR37AI020565 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI THOMAS A. PLATTS-MILLS · 1992 to 2026
$8.4M
DUST MITE, COCKROACH AND CAT ALLERGENS IN HOUSES/ASTHMAR01AI020565 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI PLATTS-MILLS, THOMAS A. · 1985 to 2017
$7.1M
NIAID NIH HHS AI-20565NIAID NIH HHS R01 AI020565Wellcome Trust 088862Wellcome Trust 088862/Z/09/ZWellcome Trust 100714
6 · The paper itself

Abstract

The ECUAVIDA birth cohort is studying the impact of exposures to soil-transmitted helminth (STH) parasites and early-life microbial exposures on the development of atopy, allergic diseases and immune responses in childhood. A total of 2404 newborns were recruited between 2006 and 2009 in a public hospital serving the rural district of Quininde, Esmeraldas Province, in a tropical region of coastal Ecuador. Detailed measurements were done around the time of the birth, at 7 and 13 months and at 2 and 3 years, and data collection is ongoing at 5 and 8 years. Data being collected include questionnaires for: sociodemographic, lifestyle, psychosocial (at 4-6 years only) and dietary (at 6-7 years only) factors; childhood morbidity and clinical outcomes; stool samples for parasites; blood samples for DNA, measurements of vaccine responses and other measures of immune function/inflammation; and anthropometrics. Allergen skin prick test reactivity is done from 2 years and measures of airway function and inflammation at 8 years.

Indexed as

Environmental ExposureAdultAsthmaChildChild, PreschoolEcuadorEczemaFemaleHelminthiasisHumansHypersensitivity, ImmediateImmunity, InnateInfantInfant, NewbornMalePregnancy

Identifiers

PMID24990475
PMCPMC4681103

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.