Evidence map›Paper›PMID 24990290›Full record

ArticleJournal of the Royal Society, Interface2014

Lung Cancer Assistant: a hybrid clinical decision support application for lung cancer care.

M Berkan Sesen, Michael D Peake, Rene Banares-Alcantara, Donald Tse, Timor Kadir, Roz Stanley, Fergus Gleeson, Michael Brady

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

M Berkan SesenDepartment of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK berkan.sesen@gmail.com.
Michael D PeakeClinical Effectiveness and Evaluation Unit, Royal College of Physicians of London, London NW1 4LE, UK Department of Respiratory Medicine, Glenfield Hospital, Leicester LE3 9QP, UK.
Rene Banares-AlcantaraDepartment of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK.
Donald TseDepartment of Clinical Radiology, Oxford University Hospitals NHS Trust, Oxford OX3 7LJ, UK.
Timor KadirMirada Medical, Oxford OX1 1BY, UK.
Roz StanleyClinical Effectiveness and Evaluation Unit, Royal College of Physicians of London, London NW1 4LE, UK.
Fergus GleesonDepartment of Clinical Radiology, Oxford University Hospitals NHS Trust, Oxford OX3 7LJ, UK.
Michael BradyDepartment of Oncology, University of Oxford, Oxford OX3 7DQ, UK.
University of Oxford · GBOxford University Hospitals NHS Trust · GBGlenfield Hospital · GBMirada Medical (United Kingdom) · GBRoyal College of Physicians · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidisciplinary team (MDT) meetings are becoming the model of care for cancer patients worldwide. While MDTs have improved the quality of cancer care, the meetings impose substantial time pressure on the members, who generally attend several such MDTs. We describe Lung Cancer Assistant (LCA), a clinical decision support (CDS) prototype designed to assist the experts in the treatment selection decisions in the lung cancer MDTs. A novel feature of LCA is its ability to provide rule-based and probabilistic decision support within a single platform. The guideline-based CDS is based on clinical guideline rules, while the probabilistic CDS is based on a Bayesian network trained on the English Lung Cancer Audit Database (LUCADA). We assess rule-based and probabilistic recommendations based on their concordances with the treatments recorded in LUCADA. Our results reveal that the guideline rule-based recommendations perform well in simulating the recorded treatments with exact and partial concordance rates of 0.57 and 0.79, respectively. On the other hand, the exact and partial concordance rates achieved with probabilistic results are relatively poorer with 0.27 and 0.76. However, probabilistic decision support fulfils a complementary role in providing accurate survival estimations. Compared to recorded treatments, both CDS approaches promote higher resection rates and multimodality treatments.

Indexed as

Decision Support Systems, ClinicalAlgorithmsBayes TheoremDatabases, FactualDecision MakingHumansLung NeoplasmsMedical OncologyPractice Guidelines as TopicProbabilitySoftwarecomputerized decision supportlung cancer caremedical informatics

Identifiers

PMID24990290
PMCPMC4233704
OpenAlexW2110712321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.