Evidence map›Paper›PMID 24989617›Full record

Observational studyBMJ open2014

Impact of infectious diseases consultation on the management of Staphylococcus aureus bacteraemia in children.

Rebecca B Saunderson, Theodore Gouliouris, Edward J Cartwright, Emma J Nickerson, Sani H Aliyu, D Roddy O'Donnell, Wilf Kelsall, D Limmathurotsakul, Sharon J Peacock, M Estée Török

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Open forum infectious diseases · 2023
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Rebecca B SaundersonDepartment of Medicine, University of Cambridge, Cambridge, UK.
Theodore GouliourisDepartment of Medicine, University of Cambridge, Cambridge, UK Department of Microbiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, UK.
Edward J CartwrightDepartment of Medicine, University of Cambridge, Cambridge, UK Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, UK.ORCID http://orcid.org/0000-0001-5666-5990
Emma J NickersonDepartment of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Sani H AliyuDepartment of Microbiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Department of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
D Roddy O'DonnellDepartment of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Wilf KelsallDepartment of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
D LimmathurotsakulMahidol Oxford Research Unit, Mahidol University, Bangkok, Thailand.
Sharon J PeacockDepartment of Medicine, University of Cambridge, Cambridge, UK Department of Microbiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, UK Wellcome Trust Sanger Institute, Hinxton, UK.
M Estée TörökDepartment of Medicine, University of Cambridge, Cambridge, UK Department of Microbiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, UK.
University of Cambridge · GBCambridge University Hospitals NHS Foundation Trust · GBMahidol University · TH

Funding

Medical Research Council G1000803
6 · The paper itself

Abstract

objectivesInfectious diseases consultation (IDC) in adults with Staphylococcus aureus bacteraemia (SAB) has been shown to improve management and outcome. The aim of this study was to evaluate the impact of IDC on the management of SAB in children. STUDY

designObservational cohort study of children with SAB.

settingCambridge University Hospitals National Health Service (NHS) Foundation Trust, a large acute NHS Trust in the UK.

participantsAll children with SAB admitted to the Cambridge University Hospitals NHS Foundation Trust between 16 July 2006 and 31 December 2012.

methodsChildren with SAB between 2006 and 31 October 2009 were managed by routine clinical care (pre-IDC group) and data were collected retrospectively by case notes review. An IDC service for SAB was introduced in November 2009. All children with SAB were reviewed regularly and data were collected prospectively (IDC group) until 31 December 2012. Baseline characteristics, quality metrics and outcome were compared between the pre-IDC group and IDC group.

resultsThere were 66 episodes of SAB in 63 children-28 patients (30 episodes) in the pre-IDC group, and 35 patients (36 episodes) in the IDC group. The median age was 3.4 years (IQR 0.2-10.7 years). Patients in the IDC group were more likely to have echocardiography performed, a removable focus of infection identified and to receive a longer course of intravenous antimicrobial therapy. There were no differences in total duration of antibiotic therapy, duration of hospital admission or outcome at 30 or 90 days following onset of SAB.

conclusionsIDC resulted in improvements in the investigation and management of SAB in children.

Indexed as

Disease ManagementReferral and ConsultationAdolescentAnti-Bacterial AgentsBacteremiaChildChild, PreschoolDimethoateFemaleFollow-Up StudiesHumansInfantInfant, NewbornMalePrognosisRetrospective StudiesAnti-Bacterial AgentsDimethoate

Identifiers

PMID24989617
PMCPMC4091395
OpenAlexW2168671586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.