ArticleCirculation research2014
Renal denervation and Symplicity HTN-3: "Dubium sapientiae initium" (doubt is the beginning of wisdom).
Article in Circulation research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of renal denervation for the management of arterial hypertension: A systematic review and meta-analysis of randomized, sham-controlled, catheter-based trials.Journal of clinical hypertension (Greenwich, Conn.) · 2020Pooled it
- Does Renal Sympathetic Denervation Impact the Outcome in Sepsis-Induced Shock? An Experimental Porcine Model.Journal of clinical medicine · 2026Article
- Efficacy and safety of extravascular renal denervation in patients with resistant hypertension: a study protocol for a pilot, single-arm, multi-center, first-in-human study.Clinical hypertension · 2026Article
- Novel Dual Endothelin Inhibitors in the Management of Resistant Hypertension.Life (Basel, Switzerland) · 2023Review
- Impact of Primary Aldosteronism in Resistant Hypertension.Current hypertension reports · 2022Review
- Advances in pathogenesis and treatment of essential hypertension.Frontiers in cardiovascular medicine · 2022Review
- Autonomic modulation of ventricular electrical activity: recent developments and clinical implications.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Review
- Afferent innervation of the ischemic kidney contributes to renal dysfunction in renovascular hypertensive rats.Pflugers Archiv : European journal of physiology · 2020Article
- New data, new studies, new hopes for renal denervation in patients with uncontrolled hypertension.International Journal of Cardiology. Hypertension · 2019Review
- Chemical renal artery denervation with appropriate phenol in spontaneously hypertensive rats.Journal of geriatric cardiology : JGC · 2018Article
- ConfidenHT™ System for Diagnostic Mapping of Renal Nerves.Current hypertension reports · 2018Review
- Renal sympathetic denervation: Ashes to ashes or rebirth from the ashes?Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Long-term renal sympathetic denervation ameliorates renal fibrosis and delays the onset of hypertension in spontaneously hypertensive rats.American journal of translational research · 2018Article
- Programmable Hypertension Control: Another Possible Indication for Implanted Pacemakers.Journal of the American Heart Association · 2017Article
- Clinical Diagnosis and Management of Resistant Hypertension.European cardiology · 2016Review
- Device-Based Therapy for Drug-Resistant Hypertension: An Update.Current hypertension reports · 2016Review
- Renal Denervation: a Field in Flux.Current hypertension reports · 2016Review
- Resistant hypertension and chronotherapy.Materia socio-medica · 2015Review
Corrections and comments
- Comment on
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
24989489What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.