Evidence map›Paper›PMID 24987952›Full record

ReviewInternational journal of molecular sciences2014

Mediterranean diet and health: food effects on gut microbiota and disease control.

Federica Del Chierico, Pamela Vernocchi, Bruno Dallapiccola, Lorenza Putignani

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 96 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03269032 nacompletednot on this mapstarted 2017, after this paper: background citation

Impact of the Mediterranean Diet on the Gut Microbiome and Symptoms of Diarrhea-Predominant Irritable Bowel Syndrome

TypeinterventionalSponsorWake Forest University Health SciencesRan2017 to 2021Enrolled10ConditionsIrritable Bowel SyndromeArmsAmerican Diet, Mediterranean-style Diet
NCT04719052 nacompletednot on this mapstarted 2021, after this paper: background citation

Mediterranean Enriched Diet for Tackling Youth Obesity

TypeinterventionalSponsorFundació EurecatRan2021 to 2023Enrolled240ConditionsObesity, Adolescent, Lifestyle, Healthy, Diet, Healthy, Cardiovascular Risk FactorArmsDiet and behavioural intervention
NCT05511337 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of Control in Oxalate and Citrate Intake on Gut Microbiota Composition in Patients With Urolithiasis: Double-blind Randomized Clinical Study

TypeinterventionalSponsorHospital Regional de Alta Especialidad de la Península de YucatánRan2022 to 2025Enrolled60ConditionsUrolithiasisArmsCaloric restriction and control oxalate and citrate foods, Caloric restriction, Real-life intervention with control oxalate and citrate foods
3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 2 syntheses or guidelines pooled it, 202 citations in OpenAlex.

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  16. Human gut microbiome, diet, and mental disorders.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Review
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Federica Del ChiericoUnit of Metagenomics, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio, Rome 400165, Italy. federica.delchierico@opbg.net.
Pamela VernocchiUnit of Metagenomics, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio, Rome 400165, Italy. pamela.vernocchi@opbg.net.
Bruno DallapiccolaScientific Directorate, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio, Rome 400165, Italy. bruno.dallapiccola@opbg.net.
Lorenza PutignaniUnit of Parasitology, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio, Rome 400165, Italy. lorenza.putignani@opbg.net.
Bambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Mediterranean diet (MD) is considered one of the healthiest dietary models. Many of the characteristic components of the MD have functional features with positive effects on health and wellness. The MD adherence, calculated through various computational scores, can lead to a reduction of the incidence of major diseases (e.g., cancers, metabolic and cardiovascular syndromes, neurodegenerative diseases, type 2 diabetes and allergy). Furthermore, eating habits are the main significant determinants of the microbial multiplicity of the gut, and dietary components influence both microbial populations and their metabolic activities from the early stages of life. For this purpose, we present a study proposal relying on the generation of individual gut microbiota maps from MD-aware children/adolescents. The maps, based on meta-omics approaches, may be considered as new tools, acting as a systems biology-based proof of evidence to evaluate MD effects on gut microbiota homeostasis. Data integration of food metabotypes and gut microbiota "enterotypes" may allow one to interpret MD adherence and its effects on health in a new way, employable for the design of targeted diets and nutraceutical interventions in childcare and clinical management of food-related diseases, whose onset has been significantly shifted early in life.

Indexed as

Diet, MediterraneanMicrobiotaCardiovascular DiseasesDiabetes MellitusHumansIntestines

Identifiers

PMID24987952
PMCPMC4139807
OpenAlexW2000785566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.